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162046-65-3

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162046-65-3 Usage

General Description

Tert-butyl 4-(chlorosulfonyl)piperazine-1-carboxylate is a chemical compound with the molecular formula C11H18ClN3O4S. It is a piperazine derivative that contains a chlorosulfonyl functional group attached to the piperazine ring. tert-butyl 4-(chlorosulfonyl)piperazine-1-carboxylate is commonly used as a building block in organic synthesis and pharmaceutical research. It has potential applications in the development of new drugs and agrochemicals due to its ability to modify the structure and properties of organic molecules. Tert-butyl 4-(chlorosulfonyl)piperazine-1-carboxylate is known for its high reactivity and versatile reactivity, making it a valuable tool for chemical synthesis and drug discovery efforts.

Check Digit Verification of cas no

The CAS Registry Mumber 162046-65-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,0,4 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 162046-65:
(8*1)+(7*6)+(6*2)+(5*0)+(4*4)+(3*6)+(2*6)+(1*5)=113
113 % 10 = 3
So 162046-65-3 is a valid CAS Registry Number.

162046-65-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-chlorosulfonylpiperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-butyl 4-(chlorosulfonyl)piperazine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:162046-65-3 SDS

162046-65-3Downstream Products

162046-65-3Relevant articles and documents

S(vi) in three-component sulfonamide synthesis: Use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki-Miyaura coupling

Wang, Xuefeng,Yang, Min,Ye, Shengqing,Kuang, Yunyan,Wu, Jie

, p. 6437 - 6441 (2021/05/19)

Sulfuric chloride is used as the source of the -SO2- group in a palladium-catalyzed three-component synthesis of sulfonamides. Suzuki-Miyaura coupling between the in situ generated sulfamoyl chlorides and boronic acids gives rise to diverse sulfonamides in moderate to high yields with excellent reaction selectivity. Although this transformation is not workable for primary amines or anilines, the results show high functional group tolerance. With the solving of the desulfonylation problem and utilization of cheap and easily accessible sulfuric chloride as the source of sulfur dioxide, redox-neutral three-component synthesis of sulfonamides is first achieved. This journal is

phenyl-propionamide derivative, preparation method and application thereof in medicine

-

Paragraph 0231; 0233; 0234; 0235; 0236, (2017/10/05)

The invention relates to a phenyl-propionamide derivative, and a preparation method and application thereof in medicine, in particular to a phenyl-propionamide derivative shown in a general formula (I), a preparation method thereof and a medicine composition comprising the derivative, a use as a k opioid receptor (KOR receptor) agonist, and an application in preparing drugs for treating and/or preventing pains and pain-related diseases. The definition of various substituent groups of the general formula (I) is same with the definition in the description. The formula is shown in the description.

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