1620556-63-9Relevant articles and documents
Transition metal-free functionalized hydration of alkynes: One-pot synthesis of fluorinated β-keto-imidates using Selectfluor
Ghosh, Arnab,Hegde, Rajeev,Makane, Vitthal B.,Sridhar, Balasubramanian,Rode, Haridas B.,Patil, Siddappa A.,Dateer, Ramesh B.
, p. 4440 - 4445 (2019)
A transition metal-free, four-component one-pot synthesis of polyfunctionalized fluorinated β-keto-imidates via the functionalized hydration of alkynes has been described. The intermediate 1,3-ketoamino moiety was obtained from easily accessible arylpropioladehyde and arlyhydroxylamine and was treated with Selectfluor delivering fluorinated β-keto-imidates. A wide variety of functional groups are tolerated under mild reaction conditions and the product applicability is highlighted.