162059-94-1

Basic information

• Product Name: Myriceric acid C
• Synonyms: Myriceric acid C
• CAS NO: 162059-94-1
• Molecular Formula: C48H60O10
• Molecular Weight: 796.98
• Mol File: 162059-94-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 890.7±65.0 °C(Predicted)
• Appearance: /
• Density: 1.30±0.1 g/cm3(Predicted)
• PKA: 4.48±0.70(Predicted)
• CAS DataBase Reference: Myriceric acid C(CAS DataBase Reference)
• NIST Chemistry Reference: Myriceric acid C(162059-94-1)
• EPA Substance Registry System: Myriceric acid C(162059-94-1)

Safety Data

• Hazardous Substances Data: 162059-94-1(Hazardous Substances Data)

Usage

General Description

Myriceric acid C is a naturally occurring chemical compound found in the plant species Myrica cerifera, commonly known as wax myrtle or bayberry. It is a triterpenoid with a very complex and unique structure that is not commonly found in other plant species. Myriceric acid C is known for its potential medicinal properties, including anti-inflammatory and antioxidant effects. It has also shown promising activity against cancer cells in some preclinical studies. Its intricate structure and bioactivity make myriceric acid C an interesting target for further research in the fields of natural products chemistry and drug discovery.

Relevant articles and documents

Endothelin receptor antagonist triterpenoid, myriceric acid A, isolated from Myrica cerifera, and structure activity relationships of its derivatives

As the first non-peptide endothelin receptor antagonist from a higher plant, a new triterpenoid, myriceric acid A (50-235) (1) was isolated from the bayberry, Myrica cerifera. Myriceric acid A (1) inhibited not only an endothelin-1-induced increase in cytosolic free Ca2+ concentration (IC50 = 11 ± 2 nM) but [125I]endothelin-1 binding in rat aortic smooth muscle cells (K(i)=66 ±15 nM). Two new related triterpenoids, myriceric acid C (6), and myriceric acid D (8), were also isolated. Furthermore, the chemical modification of these natural products led to the synthesis of sulfated derivatives (13, 14, 15) which showed 1.5 to 20 times higher affinity for endothelin receptors. The structure activity relationships of myriceric acids and their derivatives are discussed.