16206-19-2

Basic information

• Product Name: [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide
• Synonyms: [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine, 1-oxide
• CAS NO: 16206-19-2
• Molecular Formula: C₄H₄N₆O₂
• Molecular Weight: 168.1136
• Mol File: 16206-19-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 577.9°C at 760 mmHg
• Flash Point: 303.3°C
• Density: 2.7g/cm³
• Vapor Pressure: 2.36E-13mmHg at 25°C
• Refractive Index: 2.209
• CAS DataBase Reference: [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide(16206-19-2)
• EPA Substance Registry System: [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide(16206-19-2)

Safety Data

• Hazardous Substances Data: 16206-19-2(Hazardous Substances Data)

Usage

Description

[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide is a chemical compound that features an oxadiazole ring and a pyrimidine ring. This potent compound holds potential applications in the fields of medicinal chemistry and drug design. The presence of the 1-oxide functional group, which is an oxygen atom bound to the nitrogen atom at the 1 position of the pyrimidine ring, suggests that it may possess properties suitable for pharmaceutical use. It could potentially function as a bioactive agent or exhibit other therapeutic effects. However, further research and testing are necessary to fully comprehend the compound's potential uses and properties.

Uses

Used in Pharmaceutical Industry:
[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide is used as a potential bioactive agent for its possible therapeutic effects. [1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide's unique structure, which includes an oxadiazole ring and a pyrimidine ring with a 1-oxide functional group, may contribute to its effectiveness in various medicinal applications.
Used in Drug Design:
[1,2,5]oxadiazolo[3,4-d]pyrimidine-5,7-diamine 1-oxide is used as a compound in drug design due to its potential to be developed into new pharmaceuticals. Its structure may allow for the creation of novel drugs with specific therapeutic properties, pending further research and development.

Upstream product

• 24867-36-5 5-nitropyrimidine-2,4,6-triamine 
• 16206-20-5 5,7-Diamino-8-nitro-tetrazolo<1.5-c>pyrimidin 

Relevant articles and documents

Facile synthesis and NO-generating property of 4H-[1, 2, 5]oxadiazolo[3, 4-d]pyrimidine-5, 7-dione 1-oxides

4H-[1, 2, 5]Oxadiazolo[3, 4-d]pyrimidine-5, 7-dione 1-oxides (2) are conveniently prepared in high yields by the oxidative intramolecular cyclization of 6-amino-5-mtro-lH-pyrimidine-2, 4-diones (1) employing iodosylbenzene diacetate as an oxidant in the presence of lithium hydride. The generation of nitric oxide (NO) and NO-related species from 2 occurs in the presence of thiols such as AT-acetylcysteamine, cysteine, and glutathione under physiological conditions. The evidence for the NO generation derives from mechanistic interpretations for the reaction of 2 with thiols and other chemical observations.