1620677-51-1

Basic information

• Product Name: 4-bromo-2-fluoro-5-methoxybenzoic acid
• CAS NO: 1620677-51-1
• Molecular Weight: 249.036
• Mol File: 1620677-51-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-fluoro-5-methoxybenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-fluoro-5-methoxybenzoic acid(1620677-51-1)
• EPA Substance Registry System: 4-bromo-2-fluoro-5-methoxybenzoic acid(1620677-51-1)

Safety Data

• Hazardous Substances Data: 1620677-51-1(Hazardous Substances Data)

Upstream product

• 749931-20-2 4-bromo-2-fluoro-5-methoxybenzaldehyde 
• 1084801-91-1 methyl 2-fluoro-5-hydroxybenzoate 
• 51446-30-1 2-fluoro-5-hydroxybenzoic acid 

Relevant articles and documents

INHIBITORS OF ENL/AF9 YEATS

Methods and compositions for treating leukemia are disclosed. Acylated 6-aminoindoles, acylated 6-aminopyrrolopyridines and acylated 3-aminopyrrolo[3,2-c]pyridazines of the following formula inhibit ENL/AF9 YEATS and are therefore useful for treating leukemia.

BIARYL ACYL-SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS

The present invention provides compounds of Formula (Ia), and pharmaceutically acceptable salts thereof. The compounds are useful as inhibitors of voltage-gated sodium channels, in particular Nav 1.7. (Ia); as described in the specification. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention, as well as intermediates and processes useful for making the compounds.