1620777-59-4Relevant articles and documents
Novel tartrate-based guanidines for enantioselective fluorination of 1,3-Dicarbonyl and α-cyano carbonyl compounds
Zou, Liwei,Bao, Xiaoze,Zhang, Huanrui,Song, Yuming,Qu, Jingping,Wang, Baomin
, p. 1115 - 1118 (2014)
A novel library of chiral guanidines featuring the tartaric acid skeleton is easily accessed with tunable steric and electronic properties. A guanidine molecule of this library with an incorporated 2,6-diisoaniline fragment was identified as a suitable promoter for the enantioselective fluorination of 1,3-dicarbonyl and α-cyano carbonyl compounds to furnish the fluorinated product with up to 84% ee and 99% yield using N-fluorobenzenesulfonimide (NFSI) as the fluorinating agent. CSIRO 2014.