162084-63-1

Basic information

• Product Name: 2-Cyclopentene-1-carboxylicacid,ethylester,(R)-(9CI)
• Synonyms: 2-Cyclopentene-1-carboxylicacid,ethylester,(R)-(9CI)
• CAS NO: 162084-63-1
• Molecular Formula: C8H12O2
• Molecular Weight: 140.18
• Product Categories: CARBOXYLICESTER
• Mol File: 162084-63-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Cyclopentene-1-carboxylicacid,ethylester,(R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopentene-1-carboxylicacid,ethylester,(R)-(9CI)(162084-63-1)
• EPA Substance Registry System: 2-Cyclopentene-1-carboxylicacid,ethylester,(R)-(9CI)(162084-63-1)

Safety Data

• Hazardous Substances Data: 162084-63-1(Hazardous Substances Data)

Upstream product

• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 61586-79-6 ethyl (1R,2S)-2-hydroxycyclopentanecarboxylate 
• 162084-62-0 (1R,2S)-2-methylsulfanylthioxocarbonyloxycyclopentanecarboxylic acid ethyl ester 

Downstream Products

• 162238-08-6 (+)-4,4-dimethyl-3-<(R)-(2-cyclopentenyl)methoxy>-2-cyclohexenone 

Relevant articles and documents

Regioselective synthesis of α-methyl 2-methyleneglutarate via a novel lactonization-elimination rearrangement

A facile route to the α-methyl ester of 2-methyleneglutarate via a three-step sequence from 3-hydroxymethylcyclopentene is described. Regioselective formation of the monoacid from a diester precursor proceeds via a novel fluoride-mediated, tandem deprotection/rearrangement of O-silyl 2-(hydroxymethyl)dimethylglutarate.

Preparation of (R)-(2-cyclopentenyl)methanol and the first total synthesis of (8R,11R)-precapnelladiene

Enantiometrically pure (R)-(2-cyclopentenyl)methanol (2) was prepared from ethyl 2-oxocyclopentanecarboxylate. Coupling of 2 with 4,4-dimethyl-3-phenylthio-2-cyclohexenone gave an enol ether, which was converted into (8R,11H)-precapnelladiene, [α](D)19 = -70.7°, in 6 steps.