1620907-18-7Relevant academic research and scientific papers
Deacylative Alkylation vs. Photoredox Catalysis in the Synthesis of 3,3'-Bioxindoles
Esteruelas, Miguel A.,López, Ana M.,Moreno-Cabrerizo, Cristina,Nájera, Carmen,Ortega-Martínez, Aitor,Sansano, José M.
, (2020)
The synthesis of 3,3'-bioxindoles employing deacylative alkylations (DaA) in one-pot process, where the 3-bromooxindoles are generated in situ, is described. Good yields and moderate diastereoselections are obtained. By the modification of this procedure the synthesis of pure 3-bromooxindoles through a deacylative bromination (DaB) is achieved. These bromides are efficiently employed in a photoredox dimerization process to get the desired 3,3'-bioxindoles in good yields and low diastereoselections. In this single-electron-transfer (SET) mechanism the presence of a high quantum-yield iridium(III) complex ensures high conversions in short reaction times.
Catalyst-Free Halogenation of α-Diazocarbonyl Compounds with N-Halosuccinimides: Synthesis of 3-Halooxindoles or Vinyl Halides
Ma, Chaoqun,Xing, Dong,Hu, Wenhao
supporting information, p. 3134 - 3137 (2016/07/13)
A novel catalyst-free halogenative cyclization of N-aryl diazoamides with N-halosuccinimides (NXS) is reported for the synthesis of 3-halooxindoles through a carbene-free mechanism. N-Aryl diazoamides reacted with NXS under mild and catalyst-free conditio
