16210-64-3

Usage

Physical state

Bright yellow powder

Use as a building block

in the synthesis of pharmaceuticals and organic compounds

Exhibited properties

anti-inflammatory and anti-bacterial

Potential use in drug development

yes

Use as a reagent

in organic synthesis for the construction of various organic molecules

Potential as a fluorescent dye

yes

Photochromic properties

studied in the field of materials science

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 459-57-4 4-fluorobenzaldehyde 
• 84-66-2 Diethyl phthalate 

Downstream Products

• 961-21-7 2-(p-Fluorbenzyl)-indan-1,3-dion 
• 248278-47-9 2-acetyl-1-(4-fluoro-phenyl)-1,4-dihydro-2H-fluorene-3,9-dione 
• 248278-51-5 1-(4-fluoro-phenyl)-2-(3-phenyl-acryloyl)-1,4-dihydro-2H-fluorene-3,9-dione 
• 248278-55-9 1-(4-fluoro-phenyl)-2-(6-phenyl-2-thioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-1,4-dihydro-2H-fluorene-3,9-dione 
• 1026840-86-7 1-(4-fluoro-phenyl)-2-(3-oxo-5-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-7-yl)-1,4-dihydro-2H-fluorene-3,9-dione 
• 60231-39-2 2-(4-Fluoro-benzyl)-indan 
• 1072879-95-8 C₂₁H₁₅FN₄O₂S 
• 1072880-09-1 10-methyl-9-methylthio-6-(4-fluorophenyl)-6,7,10,12-tetrahydroindeno[1,2-e]pyrimido[4,5-b][1,4]diazepine-5,11-dione 
• 1240493-88-2 2-(2,2-dimethylpropanoyl)-3-(4-fluorophenyl)spiro[cyclopropane-1,2'-indan]-1',3'-dione 
• 1240493-90-6 2-(4-fluorobenzoyl)-3-(4-fluorophenyl)-2-methylspiro[cyclopropane-1,2'-indan]-1',3'-dione 

Relevant academic research and scientific papers

Interactions of Enolizable Barbiturate Dyes

The specific barbituric acid dyes 1-n-butyl-5-(2,4-dinitro-phenyl) barbituric acid and 1-n-butyl-5-{4-[(1,3-dioxo-1H-inden-(3 H)-ylidene)methyl]phenyl}barbituric acid were used to study complex formation with nucleobase derivatives and related model compo

Polymer solar cell active layer additive and preparation method thereof

The invention discloses a polymer solar cell active layer additive and a preparation method thereof. 4-fluorobenzaldehyde, 4-chlorobenzaldehyde or 4-bromobenzaldehyde and 1,3-indandione are mixed in an ethanol solution, piperidine is added, the mixture is

Leishmanicidal and cytotoxic activities and 4D-QSAR of 2-arylidene indan-1,3-diones

The indan-1,3-dione and its derivatives are important building blocks in organic synthesis and present important biological activities. Herein, the leishmanicidal and cytotoxicity evaluation of 16 2-arylidene indan-1,3-diones is described. The compounds w

Phosphine-Catalyzed Cascade Michael Addition/[4+2] Cycloaddition Reaction of Allenoates and 2-Arylidene-1,3-indanediones

The phosphine-catalyzed cascade Michael addition/[4+2] cycloaddition reaction of tetrahydrobenzofuranone-derived allenoates and 2-arylidene-1,3-indanediones has been reported, affording spirocyclic 1,3-indanedione derivatives in moderate to high yields wi

Palladium-Catalyzed Asymmetric [3+2] Cycloaddition of Vinylethylene Carbonates with 2-Arylidene-1,3-Indandiones: Synthesis of Tetrahydrofuran-Fused Spirocyclic 1,3-Indandiones

An asymmetric [3+2] cycloaddition of 2-arylidene-1,3-indandiones with vinylethylene carbonates (VECs) had been achieved in the presence of Pd2dba3·CHCl3 and axially chiral phosphoramidite ligand. The reaction of various su

Synthesis of 2,3-diaryl-2,3,4,4а-tetrahydro-5Н-indeno[1,2-c]pyridazin-5-ones

[Figure not available: see fulltext.] The reaction of 1,3-indanedione-derived donor-acceptor cyclopropanes with phenylhydrazine in the presence of catalytic amounts of scandium trifluoromethanesulfonate leads to the formation of indeno[1,2-c]pyridazine de

CLPX INHIBITORY COMPOUNDS FOR THE TREATMENT OF MULTI RESISTANT STAPHYLOCOCCUS AUREUS VIRULENCE AND FOR THE TREATMENT OF LEUKEMIA

The present invention relates to antibiotic compounds and their use as ClpX inhibitors and in the treatment of bacterial infections, such as infections with multi-resistant Staphylococcus aureas, and in the treatment of leukemia. The present invention fur

Organophosphine-catalyzed intramolecular hydroacylation of activated alkynes

We present the details of an organophosphine-catalyzed Morita-Baylis-Hillman-type reaction of activated alkynes. The outcome is an intramolecular hydroacylation of α,β-ynones leading to the formation of 1,3-cyclopenta-, cyclohepta-, and cyclooctadione-fused arenes and heteroarenes. In addition, during the course of the investigation, a phosphine-catalyzed intramolecular aldol reaction of keto-ynones via δ′[C(sp3)-H]-functionalization was discovered, and a new annulation event comprising of a ω′[C(sp3)-H]-functionalization of α,β-ynones was also uncovered. The mechanisms governing these processes have been thoroughly elucidated.

Benzylidine indane-1,3-diones: As novel urease inhibitors; synthesis, in vitro, and in silico studies

Current study deals with the evaluation of indane-1,3-dione based compounds as new class of urease inhibitors. For that purpose, benzylidine indane-1,3-diones (1–30) were synthesized and fully characterized by different spectroscopic techniques including

Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease

A simple and efficient Knoevenagel procedure for the synthesis of 2-arylidene indan-1,3-diones is herein reported. These compounds were prepared via ZrOCl2·8H2O catalyzed reactions of indan-1,3-dione with several aromatic aldehydes and using water as the