1621004-75-8Relevant academic research and scientific papers
Indium(iii) catalyzed reactions of vinyl azides and indoles
More, Atul A.,Szpilman, Alex M.
supporting information, p. 3759 - 3764 (2020/06/08)
Indium trichloride catalyzes the reaction of vinyl azides with unfunctionalized indoles to give vinyl indoles. This is the first example of displacement of the azide group by a carbon nucleophile while preserving the vinyl function. The protocol employs very mild reaction conditions and offers excellent yields of diverse 3-vinyl indoles. It is amenable to gram scale. Access to a library of 3,3′-bis(indolyl)methanes through condensation of vinyl azides with 2 equiv of an indole is demonstrated.
Solid-phase synthesis method of vinyl indole compound
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Paragraph 0030; 0032; 0033; 0034; 0059; 0060, (2019/03/08)
The invention discloses a solid-phase synthesis method of a vinyl indole compound. The solid-phase synthesis method comprises the following steps: step (1): under the protection of nitrogen gas, immersing prepared PSSS (Polystyrene Sodium Sulfonate) resin
Bronsted acid ionic liquid catalyzed facile synthesis of 3-vinylindoles through direct C3 alkenylation of indoles with simple ketones
Taheri, Amir,Liu, Changhui,Lai, Bingbing,Cheng, Cheng,Pan, Xiaojuan,Gu, Yanlong
supporting information, p. 3715 - 3719 (2014/08/05)
A direct dehydrative coupling protocol for the synthesis of 3-vinylindoles using easily available indoles and simple ketones as substrates was developed with the aid of a sulfonyl-containing Bronsted acid ionic liquid. The salient features of this protoco
