162101-31-7

Basic information

• Product Name: 2-Fluoro-4-methoxyphenylboronic acid
• Synonyms: 2-FLUORO-4-METHOXYBENZENEBORONIC ACID;2-FLUORO-4-METHOXYPHENYLBORONIC ACID;AKOS BRN-0650;2-Fluoro-4-Methoxyphenylboroni;Fluoro-4-methoxyphenylboronic acid;2-Fluoro-4-methoxyph;4-Borono-3-fluoroanisole;2-Fluoro-4-Methoxyphenylboronic acidacid
• CAS NO: 162101-31-7
• Molecular Formula: C7H8BFO3
• Molecular Weight: 169.95
• EINECS: -0
• Product Categories: blocks;BoronicAcids;FluoroCompounds;Boronic Acids & Esters;Phenyls & Phenyl-Het;Aryl;Fluorinated;Organoborons;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates;Fluorine Compounds;Boronic Acids & Esters;Phenyls & Phenyl-Het
• Mol File: 162101-31-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 291.169 °C at 760 mmHg
• Flash Point: 129.895 °C
• Appearance: off-white solid
• Density: 1.265 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: soluble in Methanol
• PKA: 8.75±0.58(Predicted)
• BRN: 9192698
• CAS DataBase Reference: 2-Fluoro-4-methoxyphenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-4-methoxyphenylboronic acid(162101-31-7)
• EPA Substance Registry System: 2-Fluoro-4-methoxyphenylboronic acid(162101-31-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-36-22
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 162101-31-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

suzuki reaction

InChI:InChI=1/C7H8BFO3/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,10-11H,1H3

Upstream product

• 121-43-7 Trimethyl borate 
• 458-50-4 1-bromo-2-fluoro-4-methoxybenzene 
• 7732-18-5 water 

Downstream Products

• 1430419-60-5 2,5-bis(2-fluoro-4-methoxyphenyl)furan 
• 1430419-55-8 2,3,5-tris(2-fluoro-4-methoxyphenyl)thiophene 
• 1430419-47-8 2,5-bis(2-fluoro-4-hydroxyphenyl)-3-methylthiophene 
• 1430419-43-4 2,5-bis(2-fluoro-4-methoxyphenyl)-3-methylthiophene 
• 1430419-33-2 2,4-bis(2-fluoro-4-methoxyphenyl)thiophene 
• 1430419-28-5 3,4-bis(2-fluoro-4-methoxyphenyl)thiophene 
• 1430419-25-2 2-(2-fluoro-4-hydroxyphenyl)-5-(4-hydroxy-2-methylphenyl)thiophene 
• 1430419-17-2 2-(2-fluoro-4-methoxyphenyl)-5-(4-methoxy-2-methylphenyl)thiophene 
• 1430419-57-0 2,3,5-tris(2-fluoro-4-hydroxyphenyl)thiophene 
• 1430419-39-8 2,3-bis(2-fluoro-4-hydroxyphenyl)thiophene 
• 1430419-35-4 2,4-bis(2-fluoro-4-hydroxyphenyl)thiophene 
• 1430419-31-0 3,4-bis(2-fluoro-4-hydroxyphenyl)thiophene 
• 1429059-29-9 2,5-bis(2-fluoro-4-hydroxyphenyl)thiophene 
• 1430419-70-7 3,4-bis(2-fluoro-4-hydroxyphenyl)furan 

Relevant articles and documents

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

A new click bioorthogonal reaction system was devised to enable the fast ligation (kON≈340 m-1 s-1) of conjugatable derivatives of a rigid cyclic diol (nopoldiol) and a carefully optimized boronic acid partner, 2-methyl-5-carboxymethylphenylboronic acid. Using NMR and fluorescence spectroscopy studies, the corresponding boronates were found to form reversibly within minutes at low micromolar concentration in water, providing submicromolar equilibrium constant (Keq≈105-106 m-1). Efficient protein conjugation under physiological conditions was demonstrated with model proteins thioredoxin and albumin, and characterized by mass spectrometry and gel electrophoresis.

COMPOUND HAVING FLUORINATED NAPHTHALENE STRUCTURE AND LIQUID CRYSTAL COMPOSITION OF SAID COMPOUND

There is provided a liquid crystal composition containing the compound represented by the general formula (1) and a liquid crystal display device that uses the liquid crystal composition. The compound represented by the general formula (1) has high Δ∈, high Tni, and good miscibility with other liquid crystal compounds. Therefore, a liquid crystal composition that has high Δ∈ and exhibits a liquid crystal phase in a wide temperature range can be obtained by using the compound represented by the general formula (1) as a component of the liquid crystal composition. Thus, the compound is very useful as a constituent component of the liquid crystal composition for liquid crystal display devices.