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162107-48-4

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162107-48-4 Usage

General Description

(R)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine is a chemical compound that belongs to the oxazolidine family. It is characterized by a structure containing a 4-ethynyl substituent and a N-Boc protecting group. (R)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine is important in organic synthesis, as it can be used as a chiral building block in the preparation of various pharmaceuticals and biologically active compounds. The presence of the N-Boc protecting group allows for selective functionalization of the oxazolidine ring, making it a versatile intermediate in the synthesis of complex molecules. Additionally, the chiral nature of (R)-2,2-Dimethyl-3-(N-Boc)-4-ethynyl-oxazolidine gives it potential applications in asymmetric synthesis and catalysis.

Check Digit Verification of cas no

The CAS Registry Mumber 162107-48-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,1,0 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 162107-48:
(8*1)+(7*6)+(6*2)+(5*1)+(4*0)+(3*7)+(2*4)+(1*8)=104
104 % 10 = 4
So 162107-48-4 is a valid CAS Registry Number.

162107-48-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl (4R)-4-ethynyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

1.2 Other means of identification

Product number -
Other names (R)-tert-Butyl 4-ethynyl-2,2-dimethyloxazolidine-3-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:162107-48-4 SDS

162107-48-4Relevant articles and documents

Synthesis of furanomycin derivatives by gold-catalyzed cycloisomerization of α-hydroxyallenes

Erdsack, Joerg,Krause, Norbert

, p. 3741 - 3750 (2007)

The novel furanomycin analogues 8 and 17 were synthesized as mixture of two diastereomers using the gold-catalyzed cycloisomerization of α-hydroxyallenes as the key step. Compared to the traditional use of stoichiometric amounts of silver salts, gold catalysis is much more efficient for the cyclization of highly functionalized substrates. Georg Thieme Verlag Stuttgart.

Synthesis of a Novel Rhizobitoxine-Like Triazole-Containing Amino Acid

Boibessot, Thibaut,Bénimèlis, David,Jean, Marion,Benfodda, Zohra,Meffre, Patrick

supporting information, p. 2685 - 2688 (2016/11/30)

The synthesis of the four stereoisomers of a new 1,2,3-triazole analogue of rhizobitoxine from serine is described. The key step is a Huisgen 1,3-dipolar cycloaddition on an ethynylglycine synthon.

INDOLE COMPOUND AS INHIBITOR OF NECROSIS

-

Paragraph 0191; 0192; 0193; 0203; 0204, (2016/08/17)

The present invention relates to an indole compound represented by formula (1), a pharmaceutically acceptable salt or isomer thereof, a composition for prevention or treatment of necrosis and necrosis-associated diseases, and a method for preparing the composition, the composition comprising the indole compound or the pharmaceutically acceptable salt or isomer thereof as an active ingredient.

A macrocyclic approach to tetracycline natural products. Investigation of transannular alkylations and Michael additions

Wzorek, Joseph S.,Kn?pfel, Thomas F.,Sapountzis, Ioannis,Evans, David A.

supporting information, p. 5840 - 5843 (2013/02/25)

A new approach to the tetracycline core structure is presented. The pivotal intermediate is identified as macrocycle III. The two interior bonds (C4a-C12a and C5a-C11a) are to be constructed through sequential transannular Michael additions (III-II) and compression-promoted transannular isoxazole alkylations from intermediate II.

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