1621167-76-7Relevant academic research and scientific papers
Synthesis of 3-ethynyl-3-hydroxy-2-oxindoles and 3-hydroxy-3-(indol-3-yl) indolin-2-ones using CuWO4 nanoparticles as recyclable heterogeneous catalyst in aqueous medium
Paplal, Banoth,Sathish, Kota,Nagaraju, Sakkani,Kashinath, Dhurke
, (2020)
A simple method for the direct activation of phenyl acetylenes (spC-H activation) and selective synthesis of 3-hydroxy-3-(indol-3-yl) indolin-2-ones and 3,3′-bis(indolyl)indolin-2-ones (via Friedel-Crafts alkylation reaction) is reported in presence of Cu
Catalytic C-H activation of arylacetylenes: A fast assembly of 3-(arylethynyl)-3-hydroxyindolin-2-ones using CuI/DBU
Chouhan, Mangilal,Senwar, Kishna Ram,Kumar, Kapil,Sharma, Ratnesh,Nair, Vipin A.
, p. 195 - 202 (2014/03/21)
A highly efficient and atom-economic methodology has been developed for the synthesis of 3-(arylethynyl)-3-hydroxyindolin-2-ones from isatins by C-H activation of arylacetylenes using a catalytic quantity of copper(I) iodide (5 mol%) and DBU (20 mol%) at 25°C, affording the products in excellent yields in very short reaction time (5 min).
