1621167-84-7Relevant academic research and scientific papers
Catalytic C-H activation of arylacetylenes: A fast assembly of 3-(arylethynyl)-3-hydroxyindolin-2-ones using CuI/DBU
Chouhan, Mangilal,Senwar, Kishna Ram,Kumar, Kapil,Sharma, Ratnesh,Nair, Vipin A.
, p. 195 - 202 (2014/03/21)
A highly efficient and atom-economic methodology has been developed for the synthesis of 3-(arylethynyl)-3-hydroxyindolin-2-ones from isatins by C-H activation of arylacetylenes using a catalytic quantity of copper(I) iodide (5 mol%) and DBU (20 mol%) at 25°C, affording the products in excellent yields in very short reaction time (5 min).
