16212-59-2

Basic information

• Product Name: (E)-3-(2-methylphenyl)-1-(pyridin-2-yl)-prop-2-en-1-one
• Synonyms: (E)-3-(2-methylphenyl)-1-(pyridin-2-yl)-prop-2-en-1-one
• CAS NO: 16212-59-2
• Molecular Weight: 223.274
• Mol File: 16212-59-2.mol

Chemical Properties

• CAS DataBase Reference: (E)-3-(2-methylphenyl)-1-(pyridin-2-yl)-prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(2-methylphenyl)-1-(pyridin-2-yl)-prop-2-en-1-one(16212-59-2)
• EPA Substance Registry System: (E)-3-(2-methylphenyl)-1-(pyridin-2-yl)-prop-2-en-1-one(16212-59-2)

Safety Data

• Hazardous Substances Data: 16212-59-2(Hazardous Substances Data)

Upstream product

• 1122-62-9 2-acetylpyridine 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 612486-01-8 2-(5-o-tolyl-4,5-dihydro-1H-pyrazol-3-yl)-pyridine 
• 1012045-26-9 4-(2'''-methylphenyl)-6-(2''-pyrazinyl)-2,2'-bipyridine 
• 158014-64-3 4′-(2′′′-toluyl)-2,2′:6′,2″-terpyridine 
• 1407183-51-0 pyridin-2-yl-((1S,2R,3R,4R)-3-(p-tolyl)bicyclo[2.2.1]hept-5-en-2-yl)methanone 
• 1414998-39-2 6,6-dimethyl-2-picolinoyl-3-o-tolyl-6,7-dihydrobenzofuran-4(5H)-one 

Relevant articles and documents

Solvent-free enantioselective conjugate addition and bioactivities of nitromethane to Chalcone containing pyridine

A series of chiral thioureas derived from quinine were tested as catalysts in the enantioselective Michael additions of nitromethane to α,β-unsaturated ketones containing pyridine. The best results were obtained with the bifunctional catalyst prepared from 3,5-di(trifluoromethyl)-aniline under solvent-free conditions. This thiourea promoted the reaction with high enantioselectivities and chemical yields for aryl ketones. The origins of enantioselectivity were further investigated via experiment and computation. Meanwhile, the products from our reaction showed potent antibacterial activities against rice bacterial leaf blight, with the S-enantiomer performing much better than the R-enantiomer. Given the promising bioactivity of this class of molecules, our work is expected to offer important applications in developing future generations for drug design.

Tuning solid emission by salts (see abstract)

The synthesis and charcterization of 4′-(2?-methylphenyl)-2,2′:6′,2″-terpyridine[4 ′-(o-CH3Ph)trpy] and 4′-(2?-trifluoromethylphenyl)-2,2′:6′,2″-terpyrid ine[4′-(o-CF3-Ph)trpy] were presented. The roles of the ortho-substituents (CH

PHARMACEUTICAL USE OF TERPYRIDINE DERIVATIVE

A terpyridine derivative represented by general formula (I) (wherein R represents hydrogen, (un)substituted phenyl, pyridyl, etc.), which has the effect of promoting the production of nerve growth factors or a neurotrophic factor activity. Hence it can be