1621367-84-7

Basic information

• Product Name: 5-amino-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide
• Synonyms: 5-amino-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide
• CAS NO: 1621367-84-7
• Molecular Weight: 269.275
• Mol File: 1621367-84-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-amino-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide(1621367-84-7)
• EPA Substance Registry System: 5-amino-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide(1621367-84-7)

Safety Data

• Hazardous Substances Data: 1621367-84-7(Hazardous Substances Data)

Upstream product

• 3863-11-4 3,4-difluoroaniline 
• 22131-51-7 5-amino-3-methyl-1,2-thiazole-4-carboxylic acid 
• 154807-47-3 5-amino-3-methyl-4-isothiazolecarboxylic acid chloride 

Downstream Products

• 1621366-91-3 6-({4-[(3,4-difluorophenyl)carbamoyl]-3-methyl-1,2-thiazol-5-yl}amino)-N-ethyl-pyrazine-2-carboxamide 
• 1621366-93-5 5-({4-[(3,4-difluorophenyl)carbamoyl]-3-methyl-1,2-thiazol-5-yl}amino)-N-methylpyrazine-2-carboxamide 
• 1621366-98-0 6-({4-[(3,4-difluorophenyl)carbamoyl]-3-methyl-1,2-thiazol-5-yl}amino)-N-methyl-pyridazine-3-carboxamide 
• 1621366-83-3 N-(3,4-difluorophenyl)-3-methyl-5-(pyrazin-2-ylamino)-1,2-thiazole-4-carboxamide 
• 1621366-45-7 5-[(4-cyanopyridin-2-yl)amino]-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide 
• 1621366-68-4 N-(3,4-difluorophenyl)-3-methyl-5-(quinoxalin-2-ylamino)-1,2-thiazole-4-carboxamide 
• 1621366-64-0 N-(3,4-difluorophenyl)-5-[(6-fluoroquinoxalin-2-yl)amino]-3-methyl-1,2-thiazole-4-carboxamide 
• 1621366-46-8 5-[(5-cyanopyridin-2-yl)amino]-N-(3,4-difluorophenyl)-3-methyl-1,2-thiazole-4-carboxamide 
• 1621366-69-5 N-(3,4-difluorophenyl)-3-methyl-5-{[4-(trifluoromethyl)-1,3-benzothiazol-2-yl]-amino}-1,2-thiazole-4-carboxamide 
• 1621366-73-1 ethyl 5-({4-[(3,4-difluorophenyl)carbamoyl]-3-methyl-1,2-thiazol-5-yl}amino)-pyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 1621366-75-3 N-(3,4-difluorophenyl)-3-methyl-5-(pyrazolo[1,5-a]pyrimidin-5-ylamino)-1,2-thiazole-4-carboxamide 
• 1621366-76-4 N-(3,4-difluorophenyl)-3-methyl-5-{[7-(trifluoromethyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]amino}-1,2-thiazole-4-carboxamide 
• 1621366-77-5 methyl 5-({4-[(3,4-difluorophenyl)carbamoyl]-3-methyl-1,2-thiazol-5-yl}amino)-pyrazine-2-carboxylate 
• 1621366-78-6 N-(3,4-difluorophenyl)-3-methyl-5-{[6-(trifluoromethyl)quinoxalin-2-yl]amino}-1,2-thiazole-4-carboxamide 

Relevant articles and documents

AMINO-SUBSTITUTED ISOTHIAZOLES

The present invention relates to amino-substituted isothiazoles of general formula (I): in which A, R1 and R2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neoplasms, as a sole agent or in combination with other active ingredients.