162148-48-3

Basic information

• Product Name: 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
• Synonyms: 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane;1,4,7,10-Tetraazacyclododecane-1,7-bis(t-butyl acetate);DO2A-t-Bu-ester(M-120);NSC 696842;1,4,7,10-Tetraazacyclododecane-1,7-diacetic acid, bis(1,1-diMethylethyl) ester;Di-tert-butyl 2,2'-(1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetate
• CAS NO: 162148-48-3
• Molecular Formula: C₂₀H₄₀N₄O₄
• Molecular Weight: 400.56
• Mol File: 162148-48-3.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 488.6 °C at 760 mmHg
• Flash Point: 249.3 °C
• Appearance: White powder
• Density: 0.998 g/cm³
• Vapor Pressure: 1.07E-09mmHg at 25°C
• Refractive Index: 1.459
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.83±0.20(Predicted)
• Water Solubility: Soluble in acetone, acetonitrile, ethyl Acetate, chloroforme, cyclohexane. Insoluble in water.
• Sensitive: Hygroscopic
• CAS DataBase Reference: 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane(162148-48-3)
• EPA Substance Registry System: 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane(162148-48-3)

Safety Data

• Hazardous Substances Data: 162148-48-3(Hazardous Substances Data)

Usage

Chemical Properties

Pale-Yellow Solid

InChI:InChI=1/C20H40N4O4/c1-19(2,3)27-17(25)15-23-11-7-21-9-13-24(14-10-22-8-12-23)16-18(26)28-20(4,5)6/h21-22H,7-16H2,1-6H3

Upstream product

• 156970-79-5 1,7-bisbenzyl-1,4,7,10-tetraazacyclododecane 
• 74199-09-0 cyclen-glyoxal 
• 38616-66-9 cyclen 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 162148-45-0 1,4,7,10-tetraaza-cyclododecane-1,7-dicarboxylic acid dibenzyl ester 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 187240-78-4 dibenzyl 4,10-bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,7-dicarboxylate 

Downstream Products

• 1276543-58-8 4,10-bis-(carbo-tert-butoxymethyl)-14-(4-aminobenzyl)-1,4,7,10-tetraazabicyclo[ 5.5.3]pentadecane 
• 1049020-10-1 1,4,7,10-tetraazacyclododecane-1,7-bis(t-butyl acetate)-4,10-bis(glutaric acid 1-tert-butyl ester-5-benzyl ester) 

Relevant articles and documents

Magnetofluorescent micellar complexes of terbium(III) as potential bimodal contrast agents for magnetic resonance and optical imaging

Terbium(iii) was coordinated to four novel 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) amphiphilic bisamide ligands. The complexes were assembled into mono-disperse micellar nano-aggregates and for the first time TbIII has b

HOCl responsive lanthanide complexes using hydroquinone caging units

Redox biology is still looking for tools to monitor redox potential in cellular biology and, despite a large and sustained effort, reliable molecular probes have yet to emerge. In contrast, molecular probes for reactive oxygen and nitrogen have been widel

DOTAM DERIVATIVES FOR THERAPEUTIC USE

The present invention relates to A compound of the formula I, in any of their stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, and the pharmaceutically acceptable salts thereof, (I) wherein M is absent or present and a positively ch