1621514-58-6

Basic information

• Product Name: 2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo[3,2-b][1,2,4]triazole
• Synonyms: 2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo[3,2-b][1,2,4]triazole
• CAS NO: 1621514-58-6
• Molecular Weight: 345.348
• Mol File: 1621514-58-6.mol

Chemical Properties

• CAS DataBase Reference: 2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo[3,2-b][1,2,4]triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo[3,2-b][1,2,4]triazole(1621514-58-6)
• EPA Substance Registry System: 2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo[3,2-b][1,2,4]triazole(1621514-58-6)

Safety Data

• Hazardous Substances Data: 1621514-58-6(Hazardous Substances Data)

Upstream product

• 383-53-9 2-bromo-1-[4-(trifluoromethyl)phenyl]ethanone 
• 3414-94-6 5-phenyl-1H-1,2,4-triazole-3-thiol 

Downstream Products

• 1621514-66-6 5-(3-methoxyphenyl)-2-phenyl-6-[4-(trifluoromethyl)phenyl]thiazolo-[3,2-b][1,2,4]triazole 
• 1621514-68-8 2-phenyl-5-(pyrimidin-5-yl)-6-[4-(trifluoromethyl)phenyl]thiazolo-[3,2-b][1,2,4]triazole 

Relevant articles and documents

First palladium-catalyzed direct regioselective C-5 (Het)arylation of mono- or disubstituted thiazolo[3,2-b][1,2,4]triazoles

An efficient and convenient method was developed for the formation of polysubstituted thiazolo[3,2-b][1,2,4]triazoles through C-5 (het)arylation. The direct C-H activation protocol giving access to di- and trisubstituted derivatives in excellent yields was optimized. The method is suitable for use with a wide range of (hetero)aryl bromides, and allows access to a collection of C-5,6 bis(het)aryl derivatives with full regioselectivity. The results are supported by a full description of all final compounds, and X-ray crystallographic data confirmed that the spectroscopic analyses were interpreted correctly. Copyright