162167-97-7

Basic information

• Product Name: 3-Aminomethyl-1-N-Boc-piperidine
• Synonyms: 1-BOC-3-AMINOMETHYLPIPERIDINE;1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOMETHYL)-, 1,1-DIMETHYLETHYL ESTER;(+/-)-1-N-BOC-PIPERIDINE-3-METHYLAMINE;1-N-BOC-3-(AMINOMETHYL)-PIPERIDINE;3-(AMINOMETHYL)-N-BOC-PIPERIDINE;3-(AMINOMETHYL)-1-N-BOC-PIPERIDINE;DL-3-AMINOMETHYL-1-N-BOC-PIPERIDINE;BOC-((R,S)-3-AMINOMETHYL)-PIPERIDINE
• CAS NO: 162167-97-7
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.3
• Product Categories: pharmacetical;Piperidine;Amines;Piperidines
• Mol File: 162167-97-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 299.4 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: off-white liquid/solid
• Density: 0.995 g/mL at 25 °C
• Vapor Pressure: 0.00119mmHg at 25°C
• Refractive Index: n20/D1.469
• Storage Temp.: Store at 0-5°C
• PKA: 10.12±0.29(Predicted)
• CAS DataBase Reference: 3-Aminomethyl-1-N-Boc-piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Aminomethyl-1-N-Boc-piperidine(162167-97-7)
• EPA Substance Registry System: 3-Aminomethyl-1-N-Boc-piperidine(162167-97-7)

Safety Data

• Hazard Codes: Xi,N,Xn
• Statements: 22-36-50/53
• Safety Statements: 26-60-61
• RIDADR: UN 3082 9 / PGIII
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 162167-97-7(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow oil

Uses

3-Aminomethyl-1-Boc-piperidine is used as pharmaceutical intermediate.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-5-9(7-12)8-13/h9H,4-8,12H2,1-3H3/p+1/t9-/m0/s1

Upstream product

• 191092-05-4 1-t-butoxycarbonyl-3-(p-toluenesulfonyloxymethyl)piperidine 
• 1178881-90-7 tert-Butyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]piperidine-1-carboxylate 
• 71962-74-8 Ethyl nipecotate 
• 91419-53-3 (+/-)-2-N-tert-butoxycabonylpiperidine-3-carbonitrile 
• 91419-49-7 tert-butyl 3-carbamoylpiperidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4138-26-5 nipecotamide 
• 274682-80-3 3-thiocarbamoylpiperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 681244-10-0 2-({[2-({[1-(tert-butoxycarbonyl)-3-piperidinyl]methyl}amino)phenyl]sulfonyl}amino)-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid 
• 478366-01-7 3-(benzyloxycarbonylamino-methyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 642443-45-6 3-[(2-chloroacetylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 642443-52-5 3-({3-[5-(3,4-dimethoxy-phenyl)-pyrimidin-2-yl]-propionylamino}-methyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 911641-04-8 1,1-dimethylethyl 3-{[(N-{[(phenylmethyl)oxy]carbonyl}-L-leucyl)amino]methyl}-1-piperidinecarboxylate 
• 914810-87-0 tert-butyl 3-{[({10-[(2,2'-dimethyl-1,1'-biphenyl-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}carbonyl)amino]methyl}piperidine-1-carboxylate 
• 323182-15-6 (2R)-N-(3-piperidylmethyl)-1-{(2S)-1-(3,3,3-triphenylpropanoyl)pyrrolidin-2-yl}carbonylpyrrolidine-2-carboxamide monohydrochloride 
• 73017-76-2 methanesulfonic acid cyclopentylmethyl ester 
• 1178881-91-8 tert-butyl 3-{[(2-methoxy-benzoyl)amino]methyl}piperidine-1-carboxylate 

Relevant articles and documents

FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of fused pyrimidine compounds of Formula I, their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to a process of preparation of these fused pyrimidine compounds, and to pharmaceutical compositions containing them.

NOVEL TRIAZOLOPYRAZINE DERIVATIVE AND USE THEREOF

The present invention relates to a novel triazolopyrazine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating hyper proliferative disorder. The present invention can be useful as a therapeutic agent for various hyper proliferative disorders associated with excessive cell proliferation and growth caused by abnormal kinase activity, such as cancer, psoriasis, rheumatoid arthritis, and diabetic retinopathy, by efficiently inhibiting c-Met tyrosine kinase activity.

3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE

[Problem] There is provided a compound useful as a preventive or remedy for cardiovascular disease, neurologic disease, metabolic disease, reproductive disease, and digestive disease. [Means for Resolution] A compound or a pharmaceutically acceptable salt