1621679-05-7

Basic information

• Product Name: 4,6-DIBROMO-2-(PROPYLTHIO)PYRIMIDIN-5-AMINE
• Synonyms: 4,6-DIBROMO-2-(PROPYLTHIO)PYRIMIDIN-5-AMINE
• CAS NO: 1621679-05-7
• Molecular Formula: C7H9Br2N3S
• Molecular Weight: 327.03946
• Mol File: 1621679-05-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,6-DIBROMO-2-(PROPYLTHIO)PYRIMIDIN-5-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIBROMO-2-(PROPYLTHIO)PYRIMIDIN-5-AMINE(1621679-05-7)
• EPA Substance Registry System: 4,6-DIBROMO-2-(PROPYLTHIO)PYRIMIDIN-5-AMINE(1621679-05-7)

Safety Data

• Hazardous Substances Data: 1621679-05-7(Hazardous Substances Data)

Upstream product

• 145783-13-7 4,6-dihydroxy-5-nitro-2-(propylthio)pyrimidine 

Downstream Products

• 274693-26-4 [3aR-[3aα,4α,6α,(1R,2S),6aα]]-2-[6-[[[7-(2-(3,4-difluorophenyl)cyclopropyl)]amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenteno-1,3-dioxolan-4-yl]oxy]ethanol 

Relevant articles and documents

For the improvement of the [...] intermediates preparation method

The invention relates to an improved preparation method for the intermediate 4, 6-dihalogen-2-(propythio)pyrimidine-5-amine used for preparing the anticoagulation drug ticagrelor, and application of the intermediate in preparation of ticagrelor. By use of a phase transfer reagent, the method reduces the halogenating reagent consumption and emission and treatment of toxic substances. Also, the obtained product has high yield and good purity. Thus, the method is a greener and more economical preparation method more suitable for industrial application.