16219-10-6

Basic information

• Product Name: (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethanol
• Synonyms: (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethanol
• CAS NO: 16219-10-6
• Molecular Weight: 383.488
• Mol File: 16219-10-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethanol(16219-10-6)
• EPA Substance Registry System: (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethanol(16219-10-6)

Safety Data

• Hazardous Substances Data: 16219-10-6(Hazardous Substances Data)

Upstream product

• 3277-89-2 phenethylmagnesium bromide 
• 15358-22-2 thevinone 

Downstream Products

• 22299-52-1 (Ξ)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-1-(toluene-4-sulfonyloxy)-ethane 
• 16196-80-8 oxo-phenyl-acetic acid (R)-1-(4,5α-epoxy-3,6-dimethoxy-17-methyl-6α,14α-etheno-morphinan-7α-yl)-ethyl ester 

Relevant articles and documents

Synthesis and evaluation of a full-agonist orvinol for PET-imaging of opioid receptors: [11C]PEO

Antagonist radiotracers have shown only a low sensitivity for detecting competition from high-efficacy agonists at opioid receptors (ORs) in vivo. We report that [11C]PEO binds with high affinity to μ and κ-opioid receptors, is a full agonist, and concentrates in brain regions of rats with a high density of the μ-OR after intravenous injection. Blocking studies with μ and κ-OR selective compounds demonstrated that the binding of [11C]PEO is saturable and selective to the μ-OR in rat brain.