162222-05-1

Upstream product

• 1694-31-1 tert-butyl acetoacetate 

Downstream Products

• 72410-67-4 tert-butyl 2-diazo-2-phenylacetate 
• 1426657-66-0 tert-butyl 2-(3-oxocyclohex-1-enyl)-2-phenylacetate 
• 1426658-03-8 tert-butyl 2-(3-oxocyclopent-1-enyl)-2-phenylacetate 
• 1432601-51-8 (S)-tert-butyl 2-(3-oxocyclohex-1-enyl)-2-phenylacetate 

Relevant academic research and scientific papers

Asymmetric Synthesis of α-Chloro-α-halo Ketones by Decarboxylative Chlorination of α-Halo-β-ketocarboxylic Acids

Chiral α-chloro-α-fluoro ketones were synthesized by enantio-selective decarboxylative chlorination of α-chloro-β-ketocarboxylic acids in the presence of a chiral amine catalyst. The reaction yielded the corresponding α-chloro-α-fluoro ketones with modera

Catalytic carbon insertion into the β-vinyl C-H bond of cyclic enones with alkyl diazoacetates

The first example of the boron Lewis acid catalyzed Csp2-H functionalization of cyclic enones was achieved using diazoacetates. The insertion of the carbon atom of diazoacetates utilizes BF3? Et2O or a newly designed oxaza

Catalytic enantioselective carbon insertion into the β-vinyl C-H bond of cyclic enones

Chiral oxazaborolidinium ion-catalyzed Csp2-H functionalization of enones using diazoacetate has been developed. Various β-substituted cyclic enones were synthesized in high yield (up to 99%) with high to excellent enantioselectivity (up to 99%