162227-13-6

Basic information

• Product Name: Hydroxy Terbinafine
• Synonyms: (5E)-2,2-Dimethyl-7-[methyl(1-naphthalenylmethyl)amino]-5-hepten-3-yn-1-ol;(5E)-
• CAS NO: 162227-13-6
• Molecular Formula: C21H25NO
• Molecular Weight: 307.43
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 162227-13-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 643.1°C at 760 mmHg
• Flash Point: 342.8°C
• Appearance: /
• Vapor Pressure: 2.97E-19mmHg at 25°C
• CAS DataBase Reference: Hydroxy Terbinafine(CAS DataBase Reference)
• NIST Chemistry Reference: Hydroxy Terbinafine(162227-13-6)
• EPA Substance Registry System: Hydroxy Terbinafine(162227-13-6)

Safety Data

• Hazardous Substances Data: 162227-13-6(Hazardous Substances Data)

Usage

Description

Hydroxy Terbinafine, a metabolite of Terbinafine, is an orally active antimycotic allylamine related to naftifine. It functions as a specific inhibitor of squalene epoxidase, a crucial enzyme in the biosynthesis of fungal ergosterol. This pale yellow oil is a promising compound with potential applications in various industries due to its unique chemical properties and antimycotic capabilities.

Uses

Used in Pharmaceutical Industry:
Hydroxy Terbinafine is used as an antimycotic agent for treating fungal infections. Its role as a specific inhibitor of squalene epoxidase makes it effective in targeting and disrupting the ergosterol biosynthesis in fungi, thereby combating the growth and proliferation of fungal pathogens.
Used in Research and Development:
In the field of research and development, Hydroxy Terbinafine is utilized as a key compound for studying the mechanisms of fungal ergosterol biosynthesis and the development of novel antimycotic drugs. Its unique properties and specificity for squalene epoxidase make it a valuable tool for understanding the underlying processes and identifying potential therapeutic targets.
Used in Drug Delivery Systems:
Hydroxy Terbinafine can be employed in the development of innovative drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. By incorporating this compound into various carriers, such as organic and metallic nanoparticles, its efficacy against fungal infections can be improved, particularly in cases of drug resistance.

InChI:InChI=1/C3H7O7P/c4-1(2(5)6)3(7)11(8,9)10/h1,3-4,7H,(H,5,6)(H2,8,9,10)/p-1