162229-27-8 Usage
General Description
DorsManin A is a naturally occurring chemical compound that is isolated from the marine sponge D. cavernosa. It is a potent inhibitor of the enzyme phosphodiesterase-4 (PDE4), which is involved in the regulation of cyclic adenosine monophosphate (cAMP) levels in cells. By inhibiting PDE4, DorsManin A can increase cAMP levels, which has been shown to have anti-inflammatory and anti-tumor properties. Research on DorsManin A is still in its early stages, but its potential therapeutic applications for conditions such as inflammatory diseases and cancer are of interest to the scientific community.
Check Digit Verification of cas no
The CAS Registry Mumber 162229-27-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,2,2,2 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 162229-27:
(8*1)+(7*6)+(6*2)+(5*2)+(4*2)+(3*9)+(2*2)+(1*7)=118
118 % 10 = 8
So 162229-27-8 is a valid CAS Registry Number.
162229-27-8Relevant articles and documents
Hemisynthesis and Spectroscopic Characterization of Three New Chalcone Derivatives from Dorstenia barteri
Ngameni, Bathelemy,Fotso, Ghislain Wabo,Ambassa, Pantaleon,Kamga, Justin,Dastan, Arif,Ngadjui, Bonaventure Tchaleu
, p. 241 - 247 (2017)
The hemisynthesis of three new chalcones, namely kenzanol, kelianol A, and kelianol B, from Dorstenia barteri (Moraceae) is described here for the first time. The synthetic pathways employed in this work involved the pyrolysis and catalytic hydrogenation of readily available and starting materials, 4-hydroxylonchocarpin and isobavachalcone, two major constituents of the herbaceous plant D. barteri. The structural elucidation of all the compounds was done by mass spectrometry, IR, UV, 1D and 2D NMR analysis, and also by comparison with previous reports.
