1622290-45-2Relevant academic research and scientific papers
Extremely fast gas/liquid reactions in flow microreactors: Carboxylation of short-lived organolithiums
Nagaki, Aiichiro,Takahashi, Yusuke,Yoshida, Jun-Ichi
supporting information, p. 7931 - 7934 (2014/07/07)
Carboxylation of short-lived organolithiums bearing electrophilic functional groups such as nitro, cyano, and alkoxycarbonyl groups with CO 2 to give carboxylic acids and active esters was accomplished in a flow microreactor system. The successful reactions indicate that gas/liquid mass transfer and the subsequent chemical reaction with CO2 are extremely fast. Carboxylation of short-lived organolithiums bearing electrophilic functional groups such as nitro, cyano, and alkoxycarbonyl groups with CO 2 to give carboxylic acids and active esters was accomplished in a flow microreactor system. The successful reactions indicate that gas/liquid mass transfer and the subsequent chemical reaction with CO2 are extremely fast (see scheme).
