162238-72-4Relevant academic research and scientific papers
Total synthesis of Taxol. 4. The final stages and completion of the synthesis
Nicolaou,Ueno,Liu,Nantermet,Yang,Renaud,Paulvannan,Chadha
, p. 653 - 659 (2007/10/02)
The total synthesis of (-)-Taxol has been achieved. Functional group manipulation of diol 2 provided the ABC ring system with the correct C9-keto, C10-acetyloxy functionality. Careful optimization allowed the oxidation of the C5-C6 alkene in 4 at C5 via a
