162239-08-9Relevant academic research and scientific papers
Total synthesis of carbocyclic nucleoside (+)-neplanocin A
Jung, Young Hoon,Kim, Seung In,Hong, Yeon Ju,Park, Sook Jin,Kang, Kyung Tae,Kim, So Yeon,Kim, In Su
, p. 1068 - 1073 (2015/01/30)
Asymmetric total synthesis of (+)-neplanocin A was concisely achieved from readily available d-galactose via the regioselective and diastereoselective amination of carbocyclic polybenzyl ether using chlorosulfonyl isocyanate and intramolecular olefin meta
Divergent synthesis of aminocyclopentitol analogues via stereoselective amination of cyclic polybenzyl ether with chlorosulfonyl isocyanate
Jung, Young Hoon,Kim, Seung In,Hong, Yeon Ju,Park, Sook Jin,Kang, Kyung Tae,Kim, So Yeon,Park, Jung Sang,Kim, In Su
supporting information, p. 1089 - 1092 (2015/05/20)
Abstract The divergent synthesis of some novel aminocyclopentitol analogues was concisely achieved from readily available d-galactose via the highly diastereoselective amination of carbocyclic polybenzyl ether using chlorosulfonyl isocyanate, diastereosel
Synthesis of β-C-galactosyl ceramide and its new aza variant via the horner-wadsworth-emmons reaction
Gorantla, Jaggaiah N.,Lankalapalli, Ravi S.
, p. 5193 - 5200 (2014/06/23)
A simple strategy for the synthesis of β-C-galactosyl ceramide and its new aza-variant analogue is described using the Horner-Wadsworth-Emmons reaction as the key step in combining the sugar and aglycone portions.
Synthesis of three C-glycoside analogues of UDP-galactopyranose as conformational probes for the mutase-catalyzed furanose/pyranose interconversion
Caravano, Audrey,Vincent, Stephane P.
experimental part, p. 1771 - 1780 (2009/09/05)
UDP-galactopyranose mutase (UGM) catalyzes the isomerization of UDP-galactopyranose (UDP-Galp) into UDP-galactofuranose (UDP-Galf), an essential step of the mycobacterial cell wall biosynthesis, Tn order to probe the UGM binding pocket, we synthesized the
Intramolecular ketonitrone-olefin cycloaddition reaction: direct and stereocontrolled synthesis of nitrogenated quaternary centered aminocyclopentitols as galactosidase inhibitors
Suman Reddy,Kadigachalam,Doddi, Venkata Ramana,Vankar, Yashwant D.
scheme or table, p. 5827 - 5830 (2010/01/11)
Synthesis of nitrogenated quaternary centered polyhydroxylated aminocyclopentanes by implementation of ketonitrone-olefin cycloaddition reaction as a key step has been accomplished in a stereocontrolled manner. The target molecules were found to be modera
Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides
Beaton, Stephen A.,Huestis, Malcolm P.,Sadeghi-Khomami, Ali,Thomas, Neil R.,Jakeman, David L.
supporting information; experimental part, p. 238 - 240 (2009/04/13)
Efficient enzymatic syntheses of isosteric phosphono analogues of sugar nucleotides have been accomplished using a thymidylyltransferase. The Royal Society of Chemistry.
Stereoselectivity in the epoxidation of carbohydrate-based oxepines
Markad, Shankar D.,Xia, Shijing,Snyder, Nicole L.,Surana, Bikash,Morton, Martha D.,Hadad, Christopher M.,Peczuh, Mark W.
, p. 6341 - 6354 (2008/12/22)
(Figure Presented) The facial selectivity in the DMDO epoxidation of carbohydrate-based oxepines derived from glucose, galactose, and mannose has been determined by product analysis and density functional theory (DFT, B3LYP/6-31+G**//B3LYP/6-31G*) calcula
SEVEN-MEMBERED RING NUCLEOSIDES
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Page/Page column 105-106, (2010/11/26)
The present invention provides nucleoside analogue Compounds that treat a host infected with a Flaviviridae virus infection, or other viruses that exhibit RNA- dependent RNA viral replication, compositions comprising" these Compounds and methods of using the Compounds for the treatment and/or Prophylaxis of viral infection, especially hepatitis C, in an infected host.
Synthesis of D-galactopyranosylphosphonic and (D-galactopyranosylmethyl) phosphonic acids as intermediates of inhibitors of galactosyltransferases
Heissigerova, Helena,Kocalka, Petr,Hlavackova, Martina,Imberty, Anne,Breton, Christelle,Chazalet, Valerie,Moravcova, Jitka
, p. 1659 - 1672 (2008/09/21)
Employing the Michaelis-Arbuzov reaction of 1-O-acetyl-2,3,4,6-tetra-O- benzyl-D-galactopyranose with triethyl phosphite and trimethylsilyl trifluoromethanesulfonate, α- and β-D-galactopyranosylphosphonic acids were prepared in 33 and 28% yields, respecti
Synthetic iminosugar derivatives as new potential immunosuppressive agents
Ye, Xin-Shan,Sun, Fang,Liu, Min,Li, Qin,Wang, Yuhang,Zhang, Guisheng,Zhang, Li-He,Zhang, Xiao-Lian
, p. 3688 - 3691 (2007/10/03)
Several iminosugar derivatives were synthesized, and their effects on the secretion of IL-4 and IFN-γ from the mouse splenocytes were examined. The effects on membrane expression of other T cell-associated molecules (CD3, CD4, CD8) and B cell-associated m
