Cas 1622400-75-2,N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide

1622400-75-2

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Basic information

Product Name: N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide
Synonyms: N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide
CAS NO:1622400-75-2
Molecular Formula:
Molecular Weight: 533.027
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide(CAS DataBase Reference)
NIST Chemistry Reference: N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide(1622400-75-2)
EPA Substance Registry System: N-(3-chloro-4-methylbenzyl)-3-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)-2,4-dioxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine-6-carboxamide(1622400-75-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1622400-75-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1622400-75-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,2,2,4,0 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1622400-75:
(9*1)+(8*6)+(7*2)+(6*2)+(5*4)+(4*0)+(3*0)+(2*7)+(1*5)=122
122 % 10 = 2
So 1622400-75-2 is a valid CAS Registry Number.

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1622400-75-2Relevant academic research and scientific papers

Discovery of novel 1,5-benzodiazepine-2,4-dione derivatives as potential anticancer agents

Chen, Yinbo,Le, Vanminh,Xu, Xiaoyong,Shao, Xusheng,Liu, Jianwen,Li, Zhong

, p. 3948 - 3951 (2014/09/03)

A series of novel 1,5-benzodiazepine-2,4-dione derivatives with C-6 amide substituents were designed and synthesized using three-component reactions. The preliminary assays showed that most of them displayed moderate to good antitumor activities against human lung carcinoma (A549), human breast epithelial carcinoma (MCF-7), human colon carcinoma (HCT116), human cervical carcinoma (Hela) and Lewis lung carcinoma (2LL). Exhilaratingly, the activity level of 6m rivaled that of 5-Fluorouracil (5-Fu) against MCF-7 cell lines, which might be used as novel lead scaffold for potential anticancer development.

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