162252-43-9Relevant academic research and scientific papers
Aromatic sialic acid analogues as potential inhibitors of influenza virus neuraminidase
Bianco, Armandodoriano,Brufani, Mario,Melchioni, Cristiana
, p. 305 - 309 (2007/10/03)
The influenza virus neuraminidase (NA) is an enzyme essential for viral infection and offers a potential target for antiviral drug development. We aimed our research at the synthesis of non-carbohydrate molecules able to inhibit NA as transition-state ana
Methods of inhibiting bacterial sialidase
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, (2008/06/13)
A method of inhibiting bacterial sialidase comprising administering to a subject an inhibiting effective amount of a compound of formula I: STR1 wherein A is CO2 H, PO2 H, or SO2 H; B is N; R1 and R2
INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE AND METHODS OF MAKING AND USING THE SAME
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, (2008/06/13)
An influenza virus neuraminidase inhibitor, its analogs, its pharmaceutically acceptable salts, derivatives, and mixtures thereof having the following formula: STR1 where A is CO 2 H, CO 2 H 3, NO 2, SO 3 H or PO 3 H 2, B is CH, N, O or S, R 1 and R 2 are
