16227-15-9

Usage

Uses

Used in Pharmaceutical Synthesis:
4,4'-Bi-4H-1,2,4-triazole is used as a building block for the synthesis of pharmaceuticals due to its unique structure and properties, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 4,4'-Bi-4H-1,2,4-triazole is utilized as a key component in the creation of new agrochemicals, enhancing crop protection and yield through its incorporation into various formulations.
Used in Materials Science:
4,4'-Bi-4H-1,2,4-triazole is employed in materials science for the development of organic semiconductors, where its electronic properties can be harnessed to improve the performance of electronic devices.
Used as a Corrosion Inhibitor:
In the field of material protection, 4,4'-Bi-4H-1,2,4-triazole serves as a corrosion inhibitor, helping to prevent the degradation of metals and alloys, thereby extending their service life and reducing maintenance costs.
Used in Antimicrobial Applications:
4,4'-Bi-4H-1,2,4-triazole has been studied for its antimicrobial properties, making it a potential candidate for use in antimicrobial agents to combat various microbial infections.
Used in Antitumor Research:
4,4'-Bi-4H-1,2,4-triazole has also been investigated for its antitumor properties, showing promise as a potential drug candidate in medicinal chemistry for the treatment of cancer.

Upstream product

• 584-13-4 4-amino-1,2,4-triazole 
• 16114-05-9 N,N'-bis(dimethylaminomethylene)hydrazine 
• 16227-06-8 {N'-[(dimethylamino)methylene]-N,N-dimethylhydrazonoformamide dihydrochloride} 
• 16227-06-8 N,N-dimethylformamide azine dihydrochloride 
• 291307-12-5 (E)-N′-((E)-(dimethylamino)methylene)-N,N-dimethylformohydrazonamide 

Relevant academic research and scientific papers

Metal-organic frameworks incorporating Cu3(μ3-OH) clusters

Interaction of 4,4′-bi(1,2,4-triazole) (btr) with copper(II) chloride (bromide) in aqueous or aqueous alcohol media led to a series of coordination polymers featuring the formation of μ 3-hydroxotricopper(II) clusters and their integration into 3D frameworks. These unprecedented structures originate in the propagation of trigonal hydroxotricopper(II) clusters bridged by tri- or tetradentate organic ligands. Complex [{Cu3(μ3-OH)}{Cu3(μ 3-O)}(μ4-btr)3(H2O) 4(OH)2Cl6]Cl·0.5H2O adopts a structure of SrSi2 topology, with eight-fold interpenetration of the coordination frameworks. The structure of [{Cu3(μ 3-OH)}2(μ3-btr)6(μ 4-btr)(μ-X)X4]X5·nH2O (X = Br, n = 6; X = Cl, n = 8) involves 2D coordination layers [{Cu 3(μ3-OH)}(μ3-btr)3] n with an exceptional (3,6)-net topology, which are cross-linked by tetradentate btr ligands and bridging chloride (bromide) ions. The Royal Society of Chemistry 2006.

The synthesis, property and reduction of high-nitrogen compound 3,3′,5,5′-tetraazido-4,4′-bis(1,2,4-triazole)

High-nitrogen compound, 3,3′,5,5′-tetraazido-4,4′-bis(1,2,4-triazole) (TABT, 83.99% N), is synthesized from sodium azide and 3,3′,5,5′-tetrabromo-4,4′-bis(1,2,4-triazole) (TBBT) which is prepared by the bromination of 4,4′-bis(1,2,4-triazole) (BTz). It is fully characterized by IR, HRMS, NMR, and single crystal X-ray diffraction showing two triazole rings of TABT perpendicular to each other. DSC and TGA are employed to study TABT's thermal stability with a decomposition temperature at 125.39?°C (onset). The calculated detonation heat of TABT and the predicted detonation velocity are 6449?kJ·kg?1and 8649?m·s?1, respectively. The reduction of TABT with hydrogen and Pd/C gave the stabilized 3,3′,5,5′-tetra(t-butyloxycarbamido)-4,4′-bis(1,2,4-triazole) (11) in the presence of (Boc)2O, providing an alternative path to the high energy density material (HDEM) TNBT [3,3′,5,5′-tetranitro-4,4′-bis(1,2,4-triazole)].

Transition metal complex compound, transition metal coordination compound using the same organic light-emitting element, color changing light-emitting element, light conversion light-emitting element, the light-emitting element of the organic laser diode, pigment laser, display device, lighting device, and electronic apparatus

Disclosed is a transition metal complex represented by the following formula (1): (wherein M represents a transition metal element; K represents an uncharged monodentate or bidentate ligand; L represents a monodentate or bidentate monoanionic or dianionic ligand; m and o represent an integer from 0 to 5; n represents an integer from 1 to 3; p represents an integer from 0 to 4; W— represents a counterion; and Y1 to Y4, R1, and R2 each independently represent a hydrogen atom, an alkyl group, a cycloalkyl group, a heterocycloalkyl group, an aryl group, an aralkyl group, a heteroaryl group, an alkenyl group, an alkynyl group, or an alkoxy group).

A simplified approach to N- and N,N′-linked 1,2,4-triazoles by transamination

A facile one-step procedure for the preparation of 4,4′-bis-1,2,4- triazole is reported. Direct transamination of N,N-dimethyl-formamide azine dihydrochloride by heating with 4-amino-1,2,4-triazole in refluxing benzene readily yields the target molecule in short duration of time with significant yield (73%). This catalyst-free method was extended to synthesise a series of 4-substituted 1,2,4-triazoles of potential interest in coordination chemistry. Georg Thieme Verlag Stuttgart.