16229-26-8Relevant academic research and scientific papers
Synthesis of thienopyrimidine-pyrazolo[3,4-b]pyridine hybrids
Park, Jae Woo,Song, Yang-Heon
, p. 281 - 285 (2017)
New hybrid compounds, thienopyrimidinyl-1H-pyrazolo[3,4-b]pyridine derivatives, were efficiently synthesized by the three-component reaction of 3-phenyl-1-(thienopyrimidin-4-yl)-1H-pyrazol-5-amine, benzoylacetonitrile and an aromatic aldehyde in the prese
Synthesis of thienotriazolopyrimidine derivatives containing triazolothiadiazole moiety
Whang, Jina,Song, Yang-Heon
, p. 603 - 607 (2013/07/19)
A series of diheterocyclic compounds 15 and 16 was synthesized by the introduction of 6-aryl or 6-benzyl-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole moiety to thieno[1,2,4]triazolo[4,3-c]pyrimidine ring through a sulfur linkage.
Facile synthesis of 2-phenylthieno[2,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as a new ring system
Song, Yang-Heon
scheme or table, p. 841 - 843 (2011/03/19)
A facile synthesis of 2-phenylthieno[2,3-e][1,2,4]triazolo[1,5-c] pyrimidine derivatives as a new ring system was presented. The compounds were prepared through a series of reaction starting with 3-aminothiophene-2- carbonitrile according to the modified
Synthesis of new sulfur-linked 1,2,4-triazolothienopyrimidine and 1,2,4-triazolopyrazolopyrimidine derivatives containing fused heterocyclic pyrimidines
Song, Yang-Heon,Son, Hoon Young
scheme or table, p. 1183 - 1187 (2010/11/16)
(Chemical Equation Presented) A series of novel bis-heterocyclic compounds 12-20 were synthesized by integrating fused heterocyclic pyrimidines, such as thienopyrimidine and pyrazolopyrimidine into the scaffold of thienotriazolopyrimidines, and pyrazolotriazolopyrimidines through a sulfur-linkage.
Discovery of novel small molecule cell type-specific enhancers of NF-κB nuclear translocation
Gong, Gangli,Xie, Yuli,Liu, Yidong,Rinderspacher, Alison,Deng, Shi-Xian,Feng, Yan,Zhu, Zhengxiang,Tang, Yufei,Wyler, Michael,Aulner, Nathalie,Toebben, Udo,Smith, Deborah H.,Branden, Lars,Chung, Caty,Schuerer, Stephan,Vidovic, Dusica,Landry, Donald W.
scheme or table, p. 1191 - 1194 (2009/08/07)
An IKKβ inhibitor reported to block NF-κB transcriptional activities in Jurkat T cells, was found to enhance NF-κB translocation in HUVEC cells. These studies suggested a noncanonical NF-κB signaling pathway independent of IKKβ in HUVEC cells.
A mild and efficient synthesis of new 3-phenyl-thienotriazolopyrimidine derivatives using iodobenzene diacetate
Joe, Byeoung Sun,Son, Hoon Young,Song, Yang-Heon
scheme or table, p. 3091 - 3097 (2009/05/27)
New 3-phenylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine 9a-i and 3-phenylthieno[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine 10a-i derivatives were easily synthesized at rt in high yield by the oxidative cyclization of thienopyrimidinyl hydrazones using iodobenzene diacetate.
FUSED HETEROCYCLIC 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
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Page/Page column 70-71, (2008/12/08)
Novel compounds are provided which are 1 1 -beta-hydroxysteroid dehydrogenase type I inhibitors. 1 1-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 1 1-beta-hydroxys
