162292-62-8Relevant academic research and scientific papers
PhI(OAc)2-mediated alkoxyoxygenation of β,γ-unsaturated ketoximes: Preparation of isoxazolines bearing two contiguous tetrasubstituted carbons
Ye, Chenghao,Kou, Xuezhen,Yang, Guoqiang,Shen, Jiefeng,Zhang, Wanbin
, p. 1148 - 1152 (2019/03/26)
A PhI(OAc)2-promoted dioxygenation of allyl oximes, including one alkoxylation, has been developed. This reaction can give isoxazoline products bearing two contiguous tetrasubstituted carbons. Various oximes substrates bearing different aryl groups and tetrasubstituted-olefin moieties were compatible with the mild reaction conditions. A two-electron oxidation pathway was proposed based on results of preliminary mechanistic studies.
Enynones in organic synthesis. 7. Substituent effects on the α-tocopherol-catalyzed cyclization of enynones to methylenecyclopentenones. Convenient syntheses of members of the methylenomycin class of antibiotics
Jacobi,Brielmann,Cann
, p. 5305 - 5316 (2007/10/02)
Substituent effects on the α-tocopherol (vitamin E, 3b) catalyzed cyclization of a wide variety of enynones 1a-z to methylenecyclopentenones 7a-z have been examined, with particular emphasis given to electron-withdrawing and -donating groups at positions
