162307-17-7

Basic information

• Product Name: Cyclopentanemethanol, 4-amino-2,3-difluoro-, (1alpha,2beta,3beta,4alpha)- (9CI)
• Synonyms: Cyclopentanemethanol, 4-amino-2,3-difluoro-, (1alpha,2beta,3beta,4alpha)- (9CI)
• CAS NO: 162307-17-7
• Molecular Formula: C6H11F2NO
• Molecular Weight: 151.1544464
• Product Categories: CYCLOPENTANE;HALIDE
• Mol File: 162307-17-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 217.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.22±0.1 g/cm3(Predicted)
• PKA: 15.05±0.10(Predicted)
• CAS DataBase Reference: Cyclopentanemethanol, 4-amino-2,3-difluoro-, (1alpha,2beta,3beta,4alpha)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanemethanol, 4-amino-2,3-difluoro-, (1alpha,2beta,3beta,4alpha)- (9CI)(162307-17-7)
• EPA Substance Registry System: Cyclopentanemethanol, 4-amino-2,3-difluoro-, (1alpha,2beta,3beta,4alpha)- (9CI)(162307-17-7)

Safety Data

• Hazardous Substances Data: 162307-17-7(Hazardous Substances Data)

Upstream product

• 49805-30-3 2-azabicyclo[2.2.1.]hept-5-en-3-one 

Relevant articles and documents

Addition of molecular fluorine to 2-azabicyclo[2.2.1]hept-5-en-3-one and related compounds: Synthesis of difluorinated carbocyclic nucleosides

Addition of molecular fluorine to bicyclo[2.2.1]hept-2-ene derivatives having electronegative substituent(s) on the ethano bridge has been found to give exo,exo-difluoro adducts with high stereoselectivity. The difluoro adducts derived from 2-azabicyclo[2.2.1]hept-5-en-3-ones having an electron-withdrawing group at 2-position were converted to the difluorinated carbocyclic nucleoside analogs.