1623120-79-5

Basic information

• Product Name: 2-AMino-4-broMo-5-Methoxy-benzoic acid
• Synonyms: 2-AMino-4-broMo-5-Methoxy-benzoic acid
• CAS NO: 1623120-79-5
• Molecular Formula: C8H8BrNO3
• Molecular Weight: 246.05802
• Mol File: 1623120-79-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 381.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.703±0.06 g/cm3(Predicted)
• PKA: 4.59±0.10(Predicted)
• CAS DataBase Reference: 2-AMino-4-broMo-5-Methoxy-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMino-4-broMo-5-Methoxy-benzoic acid(1623120-79-5)
• EPA Substance Registry System: 2-AMino-4-broMo-5-Methoxy-benzoic acid(1623120-79-5)

Safety Data

• Hazardous Substances Data: 1623120-79-5(Hazardous Substances Data)

Usage

Category

Aromatic carboxylic acids
Derivative of benzoic acid with a bromine atom at the 4th position and a methoxy group at the 5th position
Used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceuticals
Possesses unique properties for use in the production of pharmaceuticals and other organic compounds
Potential therapeutic applications due to its structural features

Upstream product

• 67-56-1 methanol 
• 224185-19-7 3-bromo-4-fluoro-6-methylnitrobenzene 
• 1220886-29-2 methyl 4-bromo-5-fluoro-2-nitrobenzoate 
• 1020717-99-0 4-bromo-5-fluoro-2-nitrobenzoic acid 
• 153556-42-4 4-bromo-3-fluorobenzoic acid 
• 1256955-36-8 methyl 2-amino-4-bromo-5-methoxybenzoate 
• 1527490-64-7 4-bromo-5-methoxy-2-nitrobenzoic acid 

Downstream Products

• 1300031-65-5 4-chloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methoxy-3-nitroquinoline 

Relevant articles and documents

Selenium-catalyzed intramolecular atom- And redox-economical transformation ofo-nitrotoluenes into anthranilic acids

Anthranilic acids (AAs) are significant basic chemicals used in pharmaceuticals, agrochemicals, dyes, fragrances,etc. Superfluous steps are always involved in obtaining AAs. Herein, we demonstrate a straightforward strategy to transform abundanto-nitrotoluenes into biologically and pharmaceutically significant AAs without any extra reductants, oxidants and protecting groups. Various sensitive groups, such as halogens, sulfide, aldehyde, pyridines, quinolines,etc., can be tolerated in this transformation. A hundred-gram-scale operation is realized efficiently with almost quantitative selenium recycling. Further mechanistic studies and DFT calculations disclosed the proposed atom-exchange processes and the key roles of the selenium species.

BICYCLIC HETEROCYCLE COMPOUNDS METHODS OF USE THEREOF FOR THE TREATMENT OF HERPES VIRUSES

The present invention relates to novel Bicyclic Heterocycle Compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, X, Y, Z, R1 R5, R6, and R7 are as defined herein. The present invention also relates to compositions comprising

SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS BROMODOMAIN INHIBITORS

The present invention provides novel substituted imidazo[4,5-c]quinoline derivatives of formula (1), which may be therapeutically useful, more particularly as Bromodomain inhibitors; (1) in which Cyi, Cy2, R1, R2/sub