1623154-48-2Relevant articles and documents
Anchored sulfonic acid on silica-layered NiFe2O4: A magnetically reusable nanocatalyst for Hantzsch synthesis of 1,4-dihydropyridines
Zeynizadeh, Behzad,Rahmani, Soleiman,Eghbali, Elham
, p. 57 - 66 (2019)
In this study, the immobilization of sulfonic acid on silica-layered nickel ferrite, NiFe2O4@SiO2@SO3H, was investigated. The sulfonated Ni-nanocatalyst was then characterized using FT-IR, SEM, EDX, XRD and VSM analyses. Catalytic activity of the Ni-nanocomposite was also studied towards Hantzsch synthesis of 1,4-dihydropyridines via one-pot condensation reaction of 1,3-diketones (ethyl acetoacetate or 4-hydroxycoumarin), aromatic aldehydes and aqueous ammonia in H2O (70 °C)as a green solvent. All reactions were carried out within 10–100 min to afford the products in high to excellent yields. The green aspect of this synthetic protocol was more studied by examining the reusability of NiFe2O4@SiO2@SO3H MNPs for seven consecutive cycles without the significant loss of catalytic activity. The current method represents remarkable advantages in terms of mild reaction conditions, using H2O as an environmental-friendly solvent, stability and easy separation of the magnetic nanocatalyst, high yield of products, wide tolerance of starting materials and the perfect reusability of the applied Ni-nanocatalyst.
Cascade synthesis of fused polycyclic dihydropyridines by Ni–Zn–Fe hydrotalcite (HT) immobilized on silica-coated magnetite as magnetically reusable nanocatalyst
Gilanizadeh, Masumeh,Zeynizadeh, Behzad
, p. 2811 - 2825 (2019)
Abstract: An efficient ecofriendly approach has been developed for one-pot multicomponent synthesis of fused polycyclic dihydropyridine (DHP) derivatives. Tandem condensation of aromatic aldehydes, 4-hydroxycoumarin, and ammonium acetate was performed usi
Guanidinium-based sulfonic acid: an efficient Br?nsted acid organocatalyst for the synthesis of fused polycyclic dihydropyridines in water
Shaabani, Ahmad,Shaabani, Shabnam,Seyyedhamzeh, Mozhdeh,Sangachin, Mona Hamidzad,Hajishaabanha, Fatemeh
, p. 7247 - 7256 (2016)
Abstract: An efficient and eco-friendly protocol for the synthesis of polycyclic dihydropyridine scaffolds has been developed from readily accessible 4-hydroxycoumarin, aldehydes, and ammonium acetate in the presence of guanidinium-based sulfonic acid as a Br?nsted acid organocatalyst. This method provides several advantages, such as simple work-up procedure, environmentally benign, recyclable catalyst, and high yields. In addition, water was chosen as a green solvent. Graphical Abstract: [Figure not available: see fulltext.]
Fe3O4?SiO2?(CH2)3-urea-quinoline sulfonic acid chloride: A novel catalyst for the synthesis of coumarin containing 1,4 dihydropyridines
Karimi, Fatemeh,Saffarian, Haniyeh,Yarie, Meysam,Zolfigol, Mohammad Ali
, (2020/10/02)
Fe3O4?SiO2?(CH2)3-urea-quinoline sulfonic acid chloride, as a novel and efficient nanomagnetic catalyst bearing urea linkers, was designed, synthesized and then fully characterized by using various te
Sulfonyl-bridged (copper-immobilized nickel ferrite) with activated montmorillonite, [(NiFe2O4@Cu)SO2(MMT)]: a new class of magnetically separable clay nanocomposite systems towards Hantzsch synthesis of coumarin-based 1,4
Zeynizadeh, Behzad,Rahmani, Soleiman
, p. 8002 - 8015 (2019/03/20)
In this study, the synthesis of a new class of magnetic clay-based nanocomposites by bridging of sulfonyl groups between copper-immobilized nickel ferrite (NiFe2O4@Cu) and activated montmorillonite is described. Synthesis of the clay
A New MCR strategy generating a collection of skeletally diverse simple molecules combinatorially
Nandi, Sibaji,Gupta, Ajay,Pal, Amarta Kumar
, p. 291 - 299 (2017/07/15)
Background: 1,4 Dihydropyridines (1,4 DHPs), chromeno[4,3-b] quinolines and pyrimido [4,5-b]quinolines are biologically and pharmaceutically important heterocycles. They are also present in many natural products. Many methods have been applied for their s
An aqua mediated facile synthesis of conformationally restricted polycyclic dihydropyridines
Kidwai, Mazaahir,Kukreja, Shuchi,Rastogi, Shweta,Singhal, Kavita,Mishra, Neeraj Kumar
, p. 605 - 609 (2014/06/23)
An economically and environmentally benign synthesis of 4-substituted-dihydropyridines (DHPs) is described from readily accessible 4-hydroxy coumarin with aldehydes and ammonium nitrate that are accelerated by exposure to microwaves. The reaction completes within a few minutes with good yields. The mechanistic detail of methodology includes Michael type addition of β-aminobenzopyran-2-one across the double bond of arylidine formed by the condensation of 4-hydroxycoumarin with aldehyde in aq. medium. The main advantages of the protocol reported here is absence of use of strong acid or expensive catalyst, good yields, easy work-up and almost no effluent generation.
An efficient 'on-water' synthesis of 1,4-dihydropyridines using Fe3O4@SiO2nanoparticles as a reusable catalyst
Dam, Binoyargha,Nandi, Sibaji,Pal, Amarta Kumar
supporting information, p. 5236 - 5240 (2015/01/09)
An 'on-water', efficient, high yielding, expeditious method has been developed for the synthesis of 1,4-dihydropyridine (1,4-DHP) derivatives via an one-pot multi-component condensation of dimedone or 4-hydroxycoumarine, aldehydes, and ammonium acetate using Fe3O4@SiO2nanoparticles as a recyclable heterogeneous catalyst. This method takes advantage of the fact that water, a green solvent is used in combination with Fe3O4@SiO2nanoparticles as catalyst which can be easily recovered magnetically and reused for further runs.
