16232-06-7Relevant academic research and scientific papers
Antimalarial activity of 2,4,6-trisubstituted pyrimidines
Agarwal, Anu,Srivastava, Kumkum,Puri,Chauhan, Prem M. S.
, p. 1881 - 1883 (2005)
A series of 2,4,6-trisubstituted pyrimidines (3a-o) was synthesized and evaluated for their in vitro antimalarial activity against P. falciparum. Out of the 15 compounds synthesized 11 compounds showed MIC in the range of 0.5-2 μg/mL. These compounds are
Synthesis, biological activities of chalcones and novel 4-acetylpyridine oximes, molecular docking of the synthesized products as acetylcholinesterase ligands
Behr, Jean-Bernard,Benazzouz-Touami, Amina,Machado-Rodrigues, Carine,Makhloufi-Chebli, Malika,Ould Lamara, Kamilia,Robert, Anthony,Terrachet-Bouaziz, Souhila
, (2021/12/22)
Heterocyclic chalcones were synthesized by reaction of 4-acetylpyridine with the corresponding aromatic aldehydes under Claisen Schmidt conditions. These chalcones were used as starting material for the synthesis of oximes in the presence of hydroxylamine
Antimalarial activity and synthesis of new trisubstituted pyrimidines
Agarwal, Anu,Srivastava, Kumkum,Puri,Chauhan, Prem M.S.
, p. 3130 - 3132 (2007/10/03)
A series of 2,4,6-trisubstituted-pyrimidines was synthesized and evaluated for their in vitro antimalarial activity against Plasmodium falciparum. Out of the 30 compounds synthesized 21 compounds showed MIC in the range of 0.5-2 μg/mL. These compounds are
