16236-62-7Relevant academic research and scientific papers
Lewis Acid-Mediated Reactions of Alkyl Azides with α,β- Unsaturated Ketones
Reddy, D. Srinivasa,Judd, Weston R.,Aube, Jeffrey
, p. 3899 - 3902 (2007/10/03)
(Matrix presented) Alkyl azides react with saturated ketones upon treatment with Lewis acids to afford ring-expansion products through the azido-Schmidt reaction, but this reaction does not proceed when α,β-unsaturated ketones are used. In this study, alk
Photochemical synthesis of spirocyclohexylisoquinolines, analogues of (±)-galanthamine and (±)-lycoramine
Missoum, Assia,Sinibaldi, Marie-Eve,Vallee-Goyet, Danielle,Gramain, Jean-Claude
, p. 453 - 466 (2007/10/03)
Photocyclization of N-arylenamides 10, 15 and 16 led efficiently to spirotricyclic δ-lactams 5, 6 and 7. Compound 7 was easily and stereospecifically transformed in two steps into spirocyclohexylisoquinolines 3 and 4 which show structural analogies with some Amaryllidaceae alkaloids, galanthamine 1 and lycoramine 2.
