1623809-03-9Relevant academic research and scientific papers
Photocatalytic Generation of N-Centered Hydrazonyl Radicals: A Strategy for Hydroamination of β,γ-Unsaturated Hydrazones
Hu, Xiao-Qiang,Chen, Jia-Rong,Wei, Qiang,Liu, Feng-Lei,Deng, Qiao-Hui,Beauchemin, André M.,Xiao, Wen-Jing
, p. 12163 - 12167 (2014)
A visible-light photocatalytic generation of N-centered hydrazonyl radicals has been accomplished for the first time. This approach allows efficient intramolecular addition of hydrazonyl radical to terminal alkenes, thus providing hydroamination and oxyamination products in good yields. Importantly, the protocol involves deprotonation of an N-H bond and photocatalytic oxidation to an N-centered radical, thus obviating the need to prepare photolabile amine precursors or the stoichiometric use of oxidizing reagents.
Organophotocatalytic Generation of N- and O-Centred Radicals Enables Aerobic Oxyamination and Dioxygenation of Alkenes
Hu, Xiao-Qiang,Chen, Jun,Chen, Jia-Rong,Yan, Dong-Mei,Xiao, Wen-Jing
supporting information, p. 14141 - 14146 (2016/09/23)
A cooperative TEMPO and photoredox catalytic strategy was applied for the first time to the direct conversion of N?H and O?H bonds into N- and O-centred radicals, enabling a general and selective oxidative radical oxyamination and dioxygenation of various
Efficient synthesis of dihydropyrazoles by halocyclization of β,γ-unsaturated hydrazones
Hu, Xiao-Qiang,Chen, Jia-Rong,Wei, Qiang,Liu, Feng-Lei,Deng, Qiao-Hui,Zou, You-Quan,Xiao, Wen-Jing
supporting information, p. 3082 - 3086 (2014/06/09)
An efficient halocyclization of β,γ-unsaturated hydrazones with N-bromosuccinimide was developed without the addition of any additives under mild reaction conditions to provide facile access to biologically important 4,5-dihydropyrazoles. Under the optimized conditions, a variety of highly substituted 4,5-dihydropyrazole derivatives were obtained in generally good yields. Moreover, this reaction can be further applied to the synthesis of pyrazoles in a one-pot fashion. Copyright
