16240-42-9Relevant articles and documents
2-Chloro-4-[[(1R,2R)-2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy
Saeed, Ashraf,Vaught, Grant M.,Gavardinas, Kostas,Matthews, Donald,Green, Jonathan E.,Losada, Pablo Garcia,Bullock, Heather A.,Calvert, Nathan A.,Patel, Nita J.,Sweetana, Stephanie A.,Krishnan, Venkatesh,Henck, Judith W.,Luz, John G.,Wang, Yong,Jadhav, Prabhakar
, p. 750 - 755 (2016)
A transdermal SARM has a potential to have therapeutic benefit through anabolic activity in muscle while sparing undesired effects of benign prostate hyperplasia (BPH) and liver-mediated decrease in HDL-C. 2-Chloro-4-[(2-hydroxy-2-methyl-cyclopentyl)amino
Synthesis of chiral hydroxylated cyclopentanones and cyclopentanes
Niidu, Allan,Paju, Anne,Eek, Margus,Mueuerisepp, Aleksander-Mati,Pehk, Tonis,Lopp, Margus
, p. 2678 - 2683 (2006)
A method for the synthesis of enantiomeric 1,3-dihydroxy and 2,3-dihydroxy cyclopentanones, starting from a commercially available 3-methyl-cyclopentane-1,2-dione 1, is described. Dione 1 was subjected to asymmetric 3-hydroxylation to afford 3-methyl-3-hydroxy-1,2-dione 2. The carbonyl groups in 2 were selectively differentiated by converting them either in dimethylacetal 5 or acetonide 6. Stereoselective reduction of those acetals by using NaBH4 afforded chiral methyl 1,2-dihydroxy cyclopentanone 9 and 1,3-dihydroxy cyclopentanone 10, respectively. The diols obtained were further converted to the corresponding diastereomeric triols 11-13 by hydride reduction.
Formation of β-Ga2O3nanorings from metal-organic frameworks and their high catalytic activity for epoxidation of alkenes
Wang, Wei Ping,Song, Le Xin,Li, Yao,Teng, Yue,Xia, Juan,Wang, Fang,Liu, Nan Ning
, p. 349 - 357 (2021/01/14)
Here we report a novel synthesis of hollow high-quality β-Ga2O3 nanorings based on an interesting structural evolution from concave Ga-MOF nanodisks. The concave low-crystallinity nanodisks were constructed by non-classical crystallization with particle a