162428-16-2

Upstream product

• 159691-84-6 (3R,5S)-<(tert-butyldiphenylsilyloxy)methyl>-4,5-dihydro-3-<2-methylene-3-(tetrahydropyran-2-yloxy)propyl>-2(3H)-furanone 
• 162518-02-7 (3R,5S)-3-(3-bromo-2-methylenepropyl)-5-<(tert-butyldiphenylsilyloxy)methyl>-4,5-dihydro-2(3H)-furanone 
• 162428-15-1 (4'S,4''S,6'S,6''S)-1,3-bis<6-<(tert-butyldiphenylsilyloxy)methyl>-2,2-dimethyl-1,3-dioxan-4-yl>-2-propanone 
• 162428-11-7 (3'R,3''R,5'S,5''S)-3',3''-(2-methylene-1,3-propanediyl)bis<5-<(tert-butyldiphenylsilyloxy)methyl>-4,5-dihydro-2(3H)-furanone> 
• 162428-14-0 (4'R,4''R,6'S,6''S)-4',4''-(2-methylene-1,3-propanediyl)bis<6-<(tert-butyldiphenylsilyloxy)methyl>-2,2-dimethyl-1,3-dioxane> 
• 162428-13-9 (2S,4R,8R,10S)-1,11-bis(tert-butyldiphenylsilyloxy)-6-methylene-2,4,8,10-undecanetetraol 
• 102717-29-3 (5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

Enantioselective Synthesis of Bis(γ-butyrolactones). Their Oxidative Degradation to Tetraols as a Key Step in Stereoselective Syntheses of 1,3,5,7,9-Pentaol Synthons for Polyhydroxylated Natural Products

The syntheses of two enatiopure skipped-chain pentaol building blocks 51 and 56 are described.They are based on a strategy which derives 1,3,7,9-tetraols from bis(γ-butyrolactones).Two equivalents of γ-lactone 17, readily available from L-glutamic acid, a