162428-32-2Relevant academic research and scientific papers
IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS
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Page/Page column 237; 241, (2022/02/28)
Compounds are provided that assemble together in vivo to form an ASGPR-binding compound that has an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein.
ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS
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Page/Page column 372; 375, (2021/08/06)
Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat disorders mediated by the extracellular protein are described.
Synthesis and Reactions of 1,2-Cyclopropanated Sugars
Ramana,Murali,Nagarajan
, p. 7694 - 7703 (2007/10/03)
Diastereospecific cyclopropanation of glycals 1, 2, 3, 4, and 41 was carried out using either dihalocarbene addition or zinc-carbenoid addition to yield 1,2-cyclopropanated sugars. Dichloroand dibromocarbenes added stereoselectively anti to the C3/s
Synthesis of 1,2-Cyclopropanated Sugars from Glycals
Murali, R.,Ramana, C. V.,Nagarajan, M.
, p. 217 - 218 (2007/10/02)
Syntheses of both forms of cyclopropanated sugars from glycals by (i) Simmons-Smith reaction and (ii) dichlorocarbene addition followed by dehalogenation are described.
