16250-90-1 Usage
Description
2-ethyl-3-phenyl-1,3-oxazolidine is a five-membered heterocyclic compound belonging to the oxazolidine family, characterized by the presence of one oxygen and one nitrogen atom. It is a valuable compound in organic chemistry due to its versatile reactivity and ability to impart chirality to organic molecules.
Uses
Used in Asymmetric Synthesis:
2-ethyl-3-phenyl-1,3-oxazolidine is used as a chiral auxiliary in asymmetric synthesis for the preparation of chiral amino alcohols and amino acids. Its unique structure and properties enable the creation of enantiomerically pure compounds, which are crucial in various chemical and pharmaceutical applications.
Used in Metal-Catalyzed Asymmetric Reactions:
In the field of catalysis, 2-ethyl-3-phenyl-1,3-oxazolidine serves as a ligand in metal-catalyzed asymmetric reactions. Its chiral nature allows for the selective formation of desired enantiomers, enhancing the efficiency and selectivity of these reactions.
Used in Pharmaceutical Industry:
2-ethyl-3-phenyl-1,3-oxazolidine is utilized as a potential building block for various drug molecules in the pharmaceutical industry. Its ability to impart chirality and its compatibility with different chemical functionalities make it a promising candidate for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 16250-90-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,5 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16250-90:
(7*1)+(6*6)+(5*2)+(4*5)+(3*0)+(2*9)+(1*0)=91
91 % 10 = 1
So 16250-90-1 is a valid CAS Registry Number.
16250-90-1Relevant articles and documents
One-Pot Synthesis of Ethyl 3-(2-Hydroxyalkyl)aminoalkanoates by Ring Opening of 1,3-Oxazolidines Using Reformatsky Reagent
Nishiyama, Tomihiro,Kishi, Hiroshi,Kitano, Kouji,Yamada, Fukiko
, p. 1765 - 1768 (2007/10/02)
Oxazolidines, obtained by the condensation of aldehydes with 2-anilino-1-alkanols, react with the Refortmatsky reagent derived from ethyl bromoacetate under mild reaction conditions to afford ethyl 3-(2-hydroxyalkyl)aminoalkanoates.
