162515-04-0Relevant articles and documents
Design, synthesis, and evaluation of 2β-alkenyl penam sulfone acids as inhibitors of β-lactamases
Richter, Hans G. F.,Angehrn, Peter,Hubschwerlen, Christian,Kania, Malgosia,Page, Malcolm G. P.,Specklin, Jean-Luc,Winkler, Fritz K.
, p. 3712 - 3722 (2007/10/03)
A general method for synthesis of 2β-alkenyl penam sulfones has been developed. The new compounds inhibited most of the common types of β- lactamase. The level of activity depended very strongly on the nature of the substituent in the 2β-alkenyl group. Th