16252-62-3 Usage
General Description
3-AMINO-1,3-DIAZASPIRO[4.4]NONANE-2,4-DIONE is a chemical compound that is a derivative of spiro nonane, containing a diazaspiro backbone and an amino group. It is a bicyclic compound with a five-membered ring and a seven-membered ring connected through a nitrogen bridge. The compound is a dione, meaning it contains two carbonyl groups, and it also contains an amino group, which can act as a base and form salts with acids. This chemical structure has potential applications in medicinal chemistry and drug design due to its unique spirocyclic framework and potential biological activity. It is important to handle this compound with care and follow proper safety protocols when working with it in a laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 16252-62-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,2,5 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16252-62:
(7*1)+(6*6)+(5*2)+(4*5)+(3*2)+(2*6)+(1*2)=93
93 % 10 = 3
So 16252-62-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3O2/c8-10-5(11)7(9-6(10)12)3-1-2-4-7/h1-4,8H2,(H,9,12)
16252-62-3Relevant articles and documents
Aminoderivatives of cycloalkanespirohydantoins: Synthesis and biological activity
Naydenova, Emilia,Pencheva, Nevena,Popova, Julita,Stoyanov, Neyko,Lazarova, Maria,Aleksiev, Boris
, p. 189 - 194 (2007/10/03)
3-Aminocycloalkanespiro-5-hydantoins were synthesized and their biological activity was studied. In contrast to hydantoins, these compounds failed to induce either anticonvulsive effects in the central nervous system or inhibitory effects on cholinergic contractions in the enteric nervous system. However, they exerted well pronounced, atropinsensitive, contractile effects on the guinea-pig ileum longitudinal muscle preparations. Structure-activity relationships established allow the assumption that: (i) the reduction of the ring size in the molecule of the spirohydantoins leads to an increase in the potency of the respective analogue to induce contractile effect; (ii) the introduction of -NH2 in position 3 increases the ability of all the compounds studied to exert contractions; (iii) the enlargement of the ring leads to: (1) an increase of the degree of desensitization of the preparations; and (2) a decrease (except 1a) of the potency of the analogues to exert contractile effects.
