1625669-62-6

Basic information

• Product Name: 4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-((tetrahydrofuran-3-yl)methyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile
• Synonyms: 4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-((tetrahydrofuran-3-yl)methyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile
• CAS NO: 1625669-62-6
• Molecular Weight: 495.501
• Mol File: 1625669-62-6.mol

Chemical Properties

• CAS DataBase Reference: 4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-((tetrahydrofuran-3-yl)methyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-((tetrahydrofuran-3-yl)methyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile(1625669-62-6)
• EPA Substance Registry System: 4-(1-(3-(trifluoromethyl)phenyl)-2,5-dioxo-3-((tetrahydrofuran-3-yl)methyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)benzonitrile(1625669-62-6)

Safety Data

• Hazardous Substances Data: 1625669-62-6(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 105-07-7 4-cyanobenzaldehyde 
• 1625672-08-3 1-((4-cyanophenyl)(2-ethoxy-6-oxocyclohex-1-enyl)methyl)-3-(3-(trifluoromethyl)-phenyl)urea 
• 13114-87-9 N-(3-trifluoromethylphenyl)urea 
• 1625672-07-2 1-((4-cyanophenyl)(2-hydroxy-6-oxocyclohex-1-enyl)methyl)-3-(3-(trifluoromethyl)-phenyl)urea 
• 51924-57-3 3-[3-(trifluoromethyl)phenyl]aminocyclohex-2-en-1-one 
• 67280-72-2 1-bromo-4-(chloro(isocyanato)methyl)benzene 
• 1625672-06-1 4-(4-bromophenyl)-1-(3-(trifluoromethyl)phenyl)-3,4,7,8-tetrahydroquinazoline-2,5(1H,6H)-dione 
• 1621272-81-8 4-(chloro(isocyanato)methyl)benzonitrile 
• 1621272-80-7 diethyl (4-cyanophenyl)methylenedicarbamate 
• 165253-29-2 3-(bromomethyl)oxolane 
• 1625675-73-1 4-(2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)-benzonitrile 

Relevant articles and documents

Substituted Bicyclic Dihydropyrimidinones And Their Use As Inhibitors Of Neutrophil Elastase Activity

This invention relates to substituted bicyclic dihydropyrimidinones of formula 1 and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.

SUBSTITUTED BICYCLIC DIHYDROPYRIMIDINONES AND THEIR USE AS INHIBITORS OF NEUTROPHIL ELASTASE ACTIVITY

This invention relates to substituted bicyclic dihydropyrimidinones of formula (1) and their use as inhibitors of neutrophil elastase activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of pulmonary, gastrointestinal and genitourinary diseases, inflammatory diseases of the skin and the eye and other autoimmune and allergic disorders, allograft rejection, and oncological diseases.