16260-26-7

Usage

Uses

Used in Pharmaceutical Industry:
Octyl myristate is used as an excipient for the formulation of pharmaceutical products, such as creams, lotions, and ointments, due to its emollient, solubilizing, and stabilizing properties.
Used in Cosmetic Industry:
In the cosmetic industry, octyl myristate is used as an emollient, solvent, and consistency agent in products like makeup, skincare, and hair care formulations. Its ability to provide a smooth and soft texture without greasiness makes it a popular choice.
Used in Food Industry:
Octyl myristate is used as an additive in the food industry, particularly in the production of flavors and fragrances, due to its ability to dissolve and stabilize these compounds.
Used in Antimicrobial Applications:
Octyl myristate exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria in vitro, making it a potential candidate for use in antimicrobial products and applications.

InChI:InChI=1/C22H44O2/c1-3-5-7-9-11-12-13-14-15-16-18-20-22(23)24-21-19-17-10-8-6-4-2/h3-21H2,1-2H3

Upstream product

• 111-87-5 octanol 
• 622-56-0 myristanilide 
• 544-63-8 n-tetradecanoic acid 

Relevant academic research and scientific papers

Esterification of Tertiary Amides by Alcohols Through C?N Bond Cleavage over CeO2

CeO2 has been found to promote ester forming alcoholysis reactions of tertiary amides. The present catalytic system is operationally simple, recyclable, and it does not require additives. The esterification process displays a wide substrate scope (>45 examples; up to 93 % isolated yield). Results of a density functional theory (DFT) study combined with in situ FT-IR observations indicate that the process proceeds through rate limiting addition of a CeO2 lattice oxygen to the carbonyl group of the adsorbed acetamide species with energy barrier of 17.0 kcal/mol. This value matches well with experimental value (17.9 kcal/mol) obtained from analysis of the Arrhenius plot. Further studies by in situ FT-IR and temperature programmed desorption using probe molecules demonstrate that both acidic and basic properties are important, and consequently, CeO2 showed the best performance for the C?N bond cleavage reaction.

Design, synthesis, antibacterial, and QSAR studies of myristic acid derivatives

A series of esters and amides of myristic acid was synthesized and tested in vitro for antibacterial activity against Gram-positive and Gram-negative bacteria. All the compounds showed activity comparable to that of the standard drug, ciprofloxacin. The structural characteristics governing antibacterial activity of myristic acid derivatives was studied using QSAR methodology. The results showed that the antibacterial activity could be modeled using the topological descriptor, valence molecular connectivity index. The predictive ability of the models was cross-validated by construction of a test set. The low residual activity and high cross-validated r2 values ( rcv2 ) observed indicated the predictive ability of the developed QSAR models.