162631-60-9Relevant academic research and scientific papers
A simple method for the oxidation of α-amino acid esters to α-oximino esters
Wu, Lisa Y.,Choi, Joseph K.,Hatton, Krit Y.,Berkman, Clifford E.
experimental part, p. 402 - 403 (2010/03/04)
Magnesium bis(monoperoxyphthalate) hexahydrate (MMPP) was found to be an effective reagent for the oxidation of various α-amino acid esters to the corresponding α-oximino acid esters. This transformation could be completed under mild conditions within 2.5 h using 1.1 equiv of MMPP in THF. Clean oximino esters were obtained after quenching and extracting the reaction from sodium thiosulfate solution. The O-phosphorylated derivative of 2-oximinoglutarate exhibited slow binding inhibitory potency for the metallopeptidase prostate-specific membrane antigen (PSMA) with an IC50 value of 58 nM.
Synthesis of nucleosides and related compounds. XXXIV. Synthesis of 5- Isonitroso-1,3-dioxane-4,6-diones and their reactions
Katagiri,Nochi,Kurimoto,Sato,Kaneko
, p. 1251 - 1257 (2007/10/02)
Synthesis of 5-isonitroso-1,3-dioxane-4,6-dione (2: isonitroso Meldrum's acid) and related compounds and their reactions were described. Compound (2) reacted with various alcohols to give hydroxyiminoacetic acid esters in moderate yields. Compound 2 was a
