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162635-04-3

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Product FOB Price Min.Order Supply Ability Supplier
Temsirolimus
Cas No: 162635-04-3
No Data 1 Gram 1 Kilogram/Week Shanghai Forever Synthesis Co.,Ltd. Contact Supplier
Temsirolimus Manufacturer/High quality/Best price/In stock
Cas No: 162635-04-3
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High quality Temsirolimus supplier in China
Cas No: 162635-04-3
No Data No Data No Data Simagchem Corporation Contact Supplier
Temsirolimus
Cas No: 162635-04-3
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
42-O-[3-Hydroxy-2-(hydroxymethyl)-2-methyl-1-oxopropyl]-rapamin
Cas No: 162635-04-3
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
162635-04-3 C56H87NO16 Temsirolimus
Cas No: 162635-04-3
No Data 1 Kilogram 100-200 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
99.6% High Purity Temsirolimus (CAS: 162635-04-3)
Cas No: 162635-04-3
No Data 100 Gram 20000 Kilogram/Day Hubei XinRunde Chemical Co., Ltd Contact Supplier
99.6% High Purity Temsirolimus (CAS: 162635-04-3)
Cas No: 162635-04-3
USD $ 1.0-2.0 / Gram 10 Gram 12 Kilogram/Day Hubei Jusheng Technology Co., Ltd., Contact Supplier
162635-04-3 Temsirolimus
Cas No: 162635-04-3
USD $ 1000.0-1000.0 / Kilogram 1 Kilogram 1 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Temsirolimus
Cas No: 162635-04-3
USD $ 1.0-1.0 / Kilogram 1 Kilogram 100000 Kilogram/Year Shanghai Upbio Tech Co.,Ltd Contact Supplier

162635-04-3 Usage

Uses

Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective acylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.

Uses

Ester analog of Rapamycin

Chemical Properties

White Solid

Uses

Temsirolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a protected bis(dihydromethyl)propionic acid, followed by deprotection. Like all tacrolimus analogues, temsirolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins. Temsirolimus is extensively cited in the literature with over 700 citations.

Uses

Temsirolimus (CCI-779) is a specific mTOR inhibitor with IC50 of 1.76 μM.
InChI:InChI=1/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3/b14-12+,17-13+,34-18+,38-26+/t33-,35-,36-,37-,39-,40+,41+,42+,44-,45+,46+,47-,49-,50+,56-/m1/s1

162635-04-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Temsirolimus

1.2 Other means of identification

Product number -
Other names CCL-779

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:162635-04-3 SDS

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