162704-76-9

Basic information

• Product Name: 4-(pyridin-3-yl)thiazole
• CAS NO: 162704-76-9
• Molecular Weight: 162.215
• Mol File: 162704-76-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(pyridin-3-yl)thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(pyridin-3-yl)thiazole(162704-76-9)
• EPA Substance Registry System: 4-(pyridin-3-yl)thiazole(162704-76-9)

Safety Data

• Hazardous Substances Data: 162704-76-9(Hazardous Substances Data)

Upstream product

• 1692-25-7 3-pyridylboronic acid 
• 34259-99-9 4-bromo-1,3-thiazole 

Relevant articles and documents

Nucleophilic C-H Etherification of Heteroarenes Enabled by Base-Catalyzed Halogen Transfer

We report a general protocol for the direct C-H etherification of N-heteroarenes. Potassium tert-butoxide catalyzes halogen transfer from 2-halothiophenes to N-heteroarenes to form N-heteroaryl halide intermediates that undergo tandem base-promoted alcohol substitution. Thus, the simple inclusion of inexpensive 2-halothiophenes enables regioselective oxidative coupling of alcohols with 1,3-azoles, pyridines, diazines, and polyazines under basic reaction conditions.