1627500-61-1

Basic information

• Product Name: (Z)-1-(3-(4-oxo-5-(4-(trifluoromethyl)benzylidene)oxazolidin-2-yl)propyl)guanidine
• CAS NO: 1627500-61-1
• Molecular Weight: 342.321
• Mol File: 1627500-61-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-1-(3-(4-oxo-5-(4-(trifluoromethyl)benzylidene)oxazolidin-2-yl)propyl)guanidine(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-(3-(4-oxo-5-(4-(trifluoromethyl)benzylidene)oxazolidin-2-yl)propyl)guanidine(1627500-61-1)
• EPA Substance Registry System: (Z)-1-(3-(4-oxo-5-(4-(trifluoromethyl)benzylidene)oxazolidin-2-yl)propyl)guanidine(1627500-61-1)

Safety Data

• Hazardous Substances Data: 1627500-61-1(Hazardous Substances Data)

Upstream product

• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 1627500-64-4 2-oxo-3-(4-(trifluoromethyl)phenyl)propanoyl chloride 
• 120658-71-1 2-oxo-3-(4-(trifluoromethyl)phenyl)propanoic acid 

Relevant articles and documents

A rapid synthesis of 4-oxazolidinones: Total synthesis of synoxazolidinones A and B

A five-step total synthesis of the marine natural product synoxazolidinone A was achieved through a diastereoselective imine acylation/cyclization cascade. Synoxazolidinone B and a series of analogues were also prepared to explore the potential of these 4-oxazolidinone natural products as antimicrobial agents. These studies confirmed the importance of the chlorine substituent for antimicrobial activity and revealed simplified dichloro derivatives that are equally potent against several bacterial strains. Synthetic synoxazolidinones: A five-step total synthesis of the marine natural product synoxazolidinone A was achieved through a diastereoselective imine acylation/cyclization cascade. Synoxazolidinone B and a series of analogues were also prepared to explore the potential of these 4-oxazolidinones as antimicrobial agents. The results revealed simplified dichloro derivatives that are equally potent against several bacterial strains.